[Acute amiodarone pulmonary toxicity with low impregnation dose: case report].

Autor: Cabrera-Rego JO; Unidad de Cuidados Coronarios Intensivos, Hospital Manuel Fajardo, La Habana, Cuba. Adress: Zapata y D, Vedado, Plaza de La Revolución, La Habana, Cuba, Código postal: 10400. Email: jocabrera@infomed.sld.cu. ORCID: 0000-0001-9372-6203., Luzurriaga Navas JD; Departamento de Imagenología, Hospital Manuel Fajardo, La Habana, Cuba. ORCID: 0000-0002-0080-2738., Yanes Quintana AA; Unidad de Cuidados Coronarios Intensivos, Hospital Manuel Fajardo, La Habana, Cuba. ORCID: 0000-0001-6576-0738.
Jazyk: Spanish; Castilian
Zdroj: Medwave [Medwave] 2020 Aug 14; Vol. 20 (7), pp. e7996. Date of Electronic Publication: 2020 Aug 14.
DOI: 10.5867/medwave.2020.07.7996
Abstrakt: Amiodarone, considered a potent antiarrhythmic, is known to cause pulmonary toxicity. Chronic interstitial pneumonitis is the most common presentation. However, acute pulmonary toxicity is rare and has a higher case fatality rate. We present a 61-year-old patient with persistent atrial fibrillation who, after a one-month treatment with oral amiodarone at a low dose impregnation of 400 mg/day, develops acute pulmonary toxicity, with radiographic and tomographic resolution after antiarrhythmic suspension and steroid treatment.
Databáze: MEDLINE