Early Pulmonary Metastasis After a Surgical Resection of Glioblastoma Multiforme. A Case Report.

Autor: Briones-Claudett KH; Faculty of Medical Sciences, University of Guayaquil, Guayaquil, Ecuador.; Physiology and Respiratory-Center Briones-Claudett, Guayaquil, Ecuador.; Intensive Care Unit, Ecuadorian Institute of Social Security (IESS), Babahoyo, Ecuador., Briones-Claudett MH; Physiology and Respiratory-Center Briones-Claudett, Guayaquil, Ecuador.; Intensive Care Unit, Ecuadorian Institute of Social Security (IESS), Babahoyo, Ecuador., Villacrés Garcia F; Intensive Care Unit, Ecuadorian Institute of Social Security (IESS), Babahoyo, Ecuador., Ortega Almeida C; Intensive Care Unit, Ecuadorian Institute of Social Security (IESS), Babahoyo, Ecuador., Escudero-Requena A; Intensive Care Unit, Ecuadorian Institute of Social Security (IESS), Babahoyo, Ecuador., Benítez Solís J; Intensive Care Unit, OMNI-Hospital, Guayaquil, Ecuador., Briones Zamora KH; Faculty of Medical Sciences, Holy Spirit University (Universidad Espíritu Santo), Samborondón, Ecuador., Briones Márquez DC; Faculty of Medical Sciences, University of Guayaquil, Guayaquil, Ecuador., Grunauer M; School of Medicine, San Francisco University of Quito (San Francisco de Quito University), Quito, Ecuador.; Pediatric Critical Care Unit, Hospital of the Valley, Quito, Ecuador.
Jazyk: angličtina
Zdroj: The American journal of case reports [Am J Case Rep] 2020 Jul 31; Vol. 21, pp. e922976. Date of Electronic Publication: 2020 Jul 31.
DOI: 10.12659/AJCR.922976
Abstrakt: BACKGROUND Glioblastoma multiforme is one of the most aggressive types of tumors that affect the central nervous system. It has an extremely high morbidity and mortality rate despite immediate treatment and advances in chemotherapy, radiotherapy, and surgery. In the natural history of the disease, extracranial metastases of glioblastoma multiforme are a rare complication that can be localized in the lungs, bone, liver, and lymph nodes. CASE REPORT A 66-year-old male presented with pulmonary metastasis after the surgical resection of a primary glioblastoma multiforme tumor. Seventeen days after surgery while in the intensive care unit, the patient had leukocytosis with a predominance of neutrophils. An exploratory bronchoscopy evidenced a white lesion that prevented the visualization of the bronchus. Consequently, a sample was taken for pathological study that demonstrated pulmonary metastasis due to glioblastoma multiforme. CONCLUSIONS Surgical resection of the tumor can precipitate the appearance of extracranial metastases, especially pulmonary metastases.
Databáze: MEDLINE