| Autor: |
Bastos PL; Secretaria Estadual de Saúde de Pernambuco. R. Dona Maria Augusta Nogueira 519, Bongi. 50751-530 Recife PE Brasil. prilunab@gmail.com., Bastos AFTL; Secretaria Estadual de Saúde de Pernambuco. R. Dona Maria Augusta Nogueira 519, Bongi. 50751-530 Recife PE Brasil. prilunab@gmail.com., Gurgel ADM; Instituto Aggeu Magalhães, Fundação Oswaldo Cruz. Recife PE Brasil., Gurgel IGD; Instituto Aggeu Magalhães, Fundação Oswaldo Cruz. Recife PE Brasil. |
| Jazyk: |
Portuguese; English |
| Zdroj: |
Ciencia & saude coletiva [Cien Saude Colet] 2020 Aug 05; Vol. 25 (8), pp. 3273-3298. |
| DOI: |
10.1590/1413-81232020258.10672018 |
| Abstrakt: |
Malathion has been widely used worldwide in arbovirus control programs. In 2015, it was classified by the International Agency for Research on Cancer (IARC) as a probable carcinogen to humans. This work aimed to systematize the evidence of the carcinogenic and mutagenic effects associated with the exposure of malathion and its analogs, malaoxon and isomalathion. The search was carried out in Toxline, PubMed and Scopus databases for original papers published from 1983 to 2015. In all, 73 papers were selected from a total of 273 eligible papers. The results of in vitro and in vivo studies showed mainly genetic and chromosomal damages caused by malathion. The epidemiological studies evidenced significant positive associations for thyroid, breast, and ovarian cancers in menopausal women. This evidence of the carcinogenic effect of malathion should be considered before its use in arbovirus control programs. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
|
