Diagnosis and clinical outcome following surgical resection of an intracranial grade III anaplastic gemistocytic astrocytoma in a cat.

Autor: Murthy VD; Veterinary Medical Teaching Hospital, University of California, Davis, CA, USA., Liepnieks ML; Comparative Pathology Laboratory, University of California, Davis, CA, USA., Roy MA; Comparative Pathology Laboratory, University of California, Davis, CA, USA., Woolard KD; Department of Pathology, Microbiology & Immunology, University of California, Davis, CA, USA., Sturges BK; Department of Surgical and Radiological Sciences, University of California, Davis, California, USA., Li CF; Department of Surgical and Radiological Sciences, University of California, Davis, California, USA.
Jazyk: angličtina
Zdroj: JFMS open reports [JFMS Open Rep] 2020 Jul 27; Vol. 6 (2), pp. 2055116920939479. Date of Electronic Publication: 2020 Jul 27 (Print Publication: 2020).
DOI: 10.1177/2055116920939479
Abstrakt: Case Summary: A 10-year-old Maine Coon cat was presented for acute onset seizures and cerebrothalamic signs. An intracranial mass, suspected to be a meningioma, was diagnosed on MRI and surgically excised. Histopathology appeared consistent with an atypical meningioma. However, following rapid regrowth of the neoplasm, the patient was humanely euthanized 3 months later. On post-mortem histopathology, the neoplasm was diagnosed as a grade III anaplastic gemistocytic astrocytoma.
Relevance and Novel Information: Gemistocytic astrocytomas are rare brain tumors in the feline patient. This case represents the first report of a feline grade III anaplastic gemistocytic astrocytoma in the cerebrum of a cat with surgical excision and recurrence. The challenging nature of ante-mortem diagnosis and the guarded prognosis, despite surgical intervention, are presented in this report.
Competing Interests: Conflict of interest: The authors declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article.
(© The Author(s) 2020.)
Databáze: MEDLINE