Tear film abnormalities in pseudoexfoliation syndrome and normal healthy participants: A comparative analysis.

Autor: Noori S; Resident, Department of Ophthalmology, Armed Forces Medical College, Pune 411040, India., Sati A; Associate Professor, Department of Ophthalmology, Armed Forces Medical College, Pune 411040, India., Moulick PS; Consultant (Ophthalmology), Command Hospital (Eastern Command), Kolkata 700027, India., Kaushik J; Associate Professor, Department of Ophthalmology, Armed Forces Medical College, Pune 411040, India., Shankar S; Associate Professor, Department of Ophthalmology, Armed Forces Medical College, Pune 411040, India., Bose R; Assistant Professor (Ophthalmology), Command Hospital (Southern Command), Pune 411040, India.
Jazyk: angličtina
Zdroj: Medical journal, Armed Forces India [Med J Armed Forces India] 2020 Jul; Vol. 76 (3), pp. 303-306. Date of Electronic Publication: 2019 May 28.
DOI: 10.1016/j.mjafi.2019.01.003
Abstrakt: Background: Pseudoexfoliative material is being implicated in causing tear film abnormalities, and the aim of the present study was to prove it and to compare with the normal healthy participants.
Methods: A total of 398 eyes of 200 participants were studied, and two groups were formed. The first, pseudoexfoliation syndrome (PEXS) group, included 198 eyes of 100 patients, and the second, age-matched control group, included 200 eyes of 100 participants. Tear film abnormalities were compared in the two groups by tear meniscus height (TMH), Schirmer test I, Schirmer test II and tear film break-up time (TBUT).
Results: On comparing the two groups using independent t-test, a significant difference was found in Schirmer test I, Schirmer test II, and TBUT between the PEXS group (Schirmer test I: 23.98 ± 10.68 mm, Schirmer test II: 17.11 ± 8.78 mm, and TBUT: 9.778 ± 5.54 s) and the age-matched control group (Schirmer test I: 27.08 ± 9.58 mm, Schirmer test II: 19.98 ± 8.48 mm, and TBUT: 13.495 ± 5.65 s) (p = 0.003 [Schirmer test I]; p = 0.001 [Schirmer test II]; and p < 0.001 [TBUT]). However, an insignificant difference was found in terms of TMH (p = 0.195) between the two groups.
Conclusion: PEXS affects tear production and leads to unstable tear film.
(© 2019 Director General, Armed Forces Medical Services. Published by Elsevier, a division of RELX India Pvt. Ltd.)
Databáze: MEDLINE
Externí odkaz: