Exercise is medicine: a new perspective for health promotion in bipolar disorder.

Autor: Sá Filho AS; Department of Physical Education, Paulista University (UNIP) , São Paulo, Brazil.; Department of Physical Education, University Center of Anápolis (Unievangélica) , Anápolis, Brazil., Cheniaux E; School of Medical Sciences, State University of Rio De Janeiro (UERJ) , Rio De Janeiro, Brazil.; Institute of Psychiatry, Federal University of Rio De Janeiro , Rio De Janeiro, Brazil., de Paula CC; Department of Cellular, Tissue and Developmental Biology, The Institute of Biomedical Science, The University of São Paulo (ICB/USP) , São Paulo, Brazil., Murillo-Rodriguez E; International Neuroscience Research Group , Yucatan, México.; Laboratorio De Neurociencias Moleculares E Integrativas, Escuela De Medicina, División Ciencias De La Salud, Universidad Anáhuac Mayab , Mérida, Mexico., Teixeira D; International Neuroscience Research Group , Yucatan, México.; Faculty of Physical Education and Sport, ULHT , Lisbon, Portugal., Monteiro D; International Neuroscience Research Group , Yucatan, México.; Research Centre in Sports, Health and Human Development, CIDESD , Rio Maior, Portugal.; Sport Science School of Rio Maior, Polytechnique Institute of Santarém , Rio Maior, Portugal., Cid L; International Neuroscience Research Group , Yucatan, México.; Research Centre in Sports, Health and Human Development, CIDESD , Rio Maior, Portugal.; Sport Science School of Rio Maior, Polytechnique Institute of Santarém , Rio Maior, Portugal., Yamamoto T; International Neuroscience Research Group , Yucatan, México.; Graduate School of Technology, Industrial and Social Sciences, Tokushima University , Tokushima, Japan., Telles-Correia D; International Neuroscience Research Group , Yucatan, México.; Clínica Universitária De Psicologia E Psiquiatria, Faculdade De Medicina, Universidade De Lisboa , Lisbon, Portugal.; Departamento De Psiquiatria, Faculdade De Medicina, Universidade De Lisboa , Lisbon, Portugal., Imperatori C; International Neuroscience Research Group , Yucatan, México.; Department of Human Sciences, European University of Rome, Via degli Aldobrandeschi 190 , Rome, Italy., Budde H; International Neuroscience Research Group , Yucatan, México.; Faculty of Human Sciences, Medical School Hamburg, University of Applied Science and Medical University , Hamburg, Germany., Machado S; Institute of Psychiatry, Federal University of Rio De Janeiro , Rio De Janeiro, Brazil.; International Neuroscience Research Group , Yucatan, México.; Laboratory of Physical Activity Neuroscience, Physical Activity Sciences Postgraduate Program, Salgado De Oliveira University (UNIVERSO) , Niterói, Brazil.; Laboratory of Physical Activity Neuroscience, Neurodiversity Institute, Queimados , RJ, Brazil.
Jazyk: angličtina
Zdroj: Expert review of neurotherapeutics [Expert Rev Neurother] 2020 Nov; Vol. 20 (11), pp. 1099-1107. Date of Electronic Publication: 2020 Aug 30.
DOI: 10.1080/14737175.2020.1807329
Abstrakt: Introduction: Similar effects in reducing the symptoms of the mood disorder are reported in the literature compared the action of drugs and aerobic exercise sessions, demonstrating the potential of exercise in the control and mood stabilization. Therefore, there are many reasons to believe that the increased cardiorespiratory fitness (VO 2max ) can be an important means of protection and a reducing potential of physical and mental damage in bipolar disorders (BD). This review will highlight the current pattern of response of exercise on the pathophysiology of BD, relating the possible mechanisms, and hypotheses based on exercises.
Areas Covered: The mechanism of monoaminergic action and its relationship with exercise, role of physical conditioning and increased VO 2Max on neurotrophin release, and new perspectives on long-term exercise will be reviewed.
Expert Opinion: The adaptations to training, although little explored in the context of BD, can induce the expression of substances that co-regulate several processes related to the pathophysiology of BD. Furthermore, high intensity interval training (HIIT) can also be adjusted to improve the physical fitness and health in patients with BD. Future research is needed to adopt a training strategy that is both time efficient and adequate for the population in question.
Databáze: MEDLINE