Incidence and exposure assessment of aflatoxins and ochratoxin A in Egyptian wheat.

Autor: Hathout AS; Food Toxicology and Contaminants Department, National Research Centre, Dokki, Cairo, Egypt., Abel-Fattah SM; Food Toxicology and Contaminants Department, National Research Centre, Dokki, Cairo, Egypt., Abou-Sree YH; Food Toxicology and Contaminants Department, National Research Centre, Dokki, Cairo, Egypt., Fouzy ASM; Food Toxicology and Contaminants Department, National Research Centre, Dokki, Cairo, Egypt.
Jazyk: angličtina
Zdroj: Toxicology reports [Toxicol Rep] 2020 Jul 15; Vol. 7, pp. 867-873. Date of Electronic Publication: 2020 Jul 15 (Print Publication: 2020).
DOI: 10.1016/j.toxrep.2020.07.003
Abstrakt: Aflatoxins and ochratoxin A occur frequently in grains and are associated with carcinogenic, and nephrotoxic properties. Therefore, the aim of this study was to determine the level of aflatoxins and ochratoxin A contamination in wheat samples obtained from different Egyptian governorates and to assess the effect of gamma irradiation on AFB 1 in spiked wheat samples, as well as to evaluate the estimated daily intake and hazard index. Thirty-six wheat grain samples purchased from different sale points were analyzed by High-Performance Liquid Chromatography. Data revealed that 33.33 % of the wheat grain samples were contaminated by aflatoxin B 1 , whereas only 16.66 % of the wheat samples were above the maximum limits (2 μg/kg) set by the European Commission. Ochratoxin A was only detected in two wheat grain samples, and the results were considered below the maximum limit (5 μg/kg) set by the European Commission. On studying the effect of gamma irradiation on wheat samples spiked by aflatoxin B 1 (20 μg/kg), results revealed that aflatoxin B 1 was reduced to 1.22 and 0.94 μg/kg for samples gamma-irradiated at a dose of 10 and 20 KGy respectively. Estimated daily intake of ochratoxin A in wheat samples was found to be higher than that of the tolerable daily intake; however, hazard index values were below one, thus demonstrating no threat to human health.
Competing Interests: The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.
(© 2020 The Author(s).)
Databáze: MEDLINE
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