Gestational diabetes mellitus yesterday, today and tomorrow: A 13 year italian cohort study.

Autor: Bordin P; Department of Prevention, ASUFC Azienda Sanitaria Universitaria Friuli Centrale, Italy., Dotto L; Diabetes Clinic, Department of Internal Medicine, ASUFC Azienda Sanitaria Universitaria Friuli Centrale, San Antonio Hospital, San Daniele del Friuli, Italy., Battistella L; Unit of Obstetrics and Gynechology, AAS3 'Alto Friuli-Collinare-Medio Friuli' San Antonio Hospital, San Daniele del Friuli, Italy., Rosso E; Diabetes Clinic, Department of Internal Medicine, ASUFC Azienda Sanitaria Universitaria Friuli Centrale, San Antonio Hospital, San Daniele del Friuli, Italy., Pecci L; Unit of Obstetrics and Gynechology, AAS3 'Alto Friuli-Collinare-Medio Friuli' San Antonio Hospital, San Daniele del Friuli, Italy., Valent F; Unit of Hygiene and Clinical Epidemiology, ASUFC Azienda Sanitaria Universitaria Friuli Centrale, Udine, Italy. Electronic address: francesca.valent@asufc.sanita.fvg.it., Collarile P; Department of Prevention, ASUFC Azienda Sanitaria Universitaria Friuli Centrale, Italy., Vanin M; Unit of Obstetrics and Gynechology, AAS3 'Alto Friuli-Collinare-Medio Friuli' San Antonio Hospital, San Daniele del Friuli, Italy.
Jazyk: angličtina
Zdroj: Diabetes research and clinical practice [Diabetes Res Clin Pract] 2020 Sep; Vol. 167, pp. 108360. Date of Electronic Publication: 2020 Aug 03.
DOI: 10.1016/j.diabres.2020.108360
Abstrakt: Aims: To describe all cases of gestational diabetes mellitus (GDM) managed at the Italian Hospital of San Daniele del Friuli from 2006 to 2018, after the establishment of a dedicated multidisciplinary team.
Methods: Data on mothers, pregnancies, and newborns have been recorded since the team establishment. The associations of maternal, pregnancy, and delivery characteristics with complications of pregnancy and delivery and adverse birth outcomes were assessed.
Results: 894 cases of GDM were observed, representing 6.8% of all deliveries. More than 20% of women were non-Italian, 5.3% had a previous macrosomic child, 12.5% previous diabetes or GDM, 27.3% family history of diabetes. On average, women had 4 visits at the clinic; mean glycated hemoglobin was 5.3%; starting body mass index (BMI) 26.2 and weight gain 10.3 kg. Cesarean sections were 21.8%. Pre-eclampsia was the most common pregnancy complication (4.7%). 6.0% of newborns were macrosomic and there were 3 fetal deaths. Only 26.3% of women had a post-partum oral glucose tolerance test. Initial BMI, weight gain, nationality, family history of diabetes or previous diabetes-related pregnancy complications were associated with pregnancy complications or adverse outcomes.
Conclusions: We identified factors to be targeted for preventing GDM complications. Further efforts should be directed at post-partum.
Competing Interests: Declaration of Competing Interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.
(Copyright © 2020 Elsevier B.V. All rights reserved.)
Databáze: MEDLINE
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