A basic MRI anatomy of the rat brain in coronal sections for practical guidance to neuroscientists.

Autor: Marinković I; Clinical Neuroscience, Neurology, Helsinki University Hospital, Haartmaninkatu 4, 00290 Helsinki, Finland. Electronic address: Ivan.Marinkovic@hus.fi., Tatlisumak T; Department of Clinical Neuroscience, Institute of Neuroscience and Physiology, Sahlgrenska Academy at University of Gothenburg, Blå Stråket 7, Plan 3, Sahlgrenska 41345, Gothenburg, Sweden; Department of Neurology, Sahlgrenska University Hospital, Blå Stråket 7, Plan 3, Sahlgrenska 41345, Gothenburg, Sweden. Electronic address: turgut.tatlisumak@neuro.gu.se., Abo-Ramadan U; VTT Technical Research Centre of Finland Ltd, University of Helsinki, Tietotie 4E, 02150 Espoo, Finland., Brkić BG; Department of CT and MRI, Sveti Sava Hospital, University of Belgrade, Belgrade, Serbia., Aksić M; Department of Neuroanatomy, Institute of Anatomy, Faculty of Medicine, University of Belgrade, Belgrade, Serbia., Marinković S; Department of Neuroanatomy, Institute of Anatomy, Faculty of Medicine, University of Belgrade, Belgrade, Serbia. Electronic address: slobodan.marinkovic@med.bg.ac.rs.
Jazyk: angličtina
Zdroj: Brain research [Brain Res] 2020 Nov 15; Vol. 1747, pp. 147021. Date of Electronic Publication: 2020 Aug 02.
DOI: 10.1016/j.brainres.2020.147021
Abstrakt: Identification of the brain structures in the magnetic resonance imaging (MRI) of the rat is very important for the experimental work of many neuroscientists. Our intention was to recognize most of the structures without overlapping the MRI sections with the histological templates. Three live rats were used for this study who were examined in a micro-MRI apparatus by performing T2-weighted sequences in serial brain sections. Most of the white matter structures were easily identified, e.g. the anterior commissure, corpus callosum with forceps minor and major, cingulum, external and internal capsules, fornix, stria medullaris and terminalis, cranial nerves, mammillothalamic tract, fasciculus retroflexus, medial and lateral lemniscus, posterior commissure, commissures of the superior and inferior colliculi, medial longitudinal fasciculus, and the cerebral peduncle. Large and small gray matter structures were recognized as well, for example, the anterior olfactory structures, nucleus accumbens, caudate putamen, claustrum, bed nucleus of the stria terminalis, pituitary gland, globus pallidus, amygdala, some midline and intralaminar thalamic nuclei, certain hypothalamic nuclei, hippocampal formation, pineal body, periaqueductal gray matter, lateral and medial geniculate bodies, superior and inferior colliculi, and cranial nerves nuclei. All in all, of the total 160 recognized brain structures, 77 were identified without using the corresponding histological atlases. We believe that our labeled MRI pictures could be an important way for quick orientation for evaluating the effects of the experimental work regarding the rat brain.
Competing Interests: Declaration of Competing Interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.
(Copyright © 2020 Elsevier B.V. All rights reserved.)
Databáze: MEDLINE
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