Pediatric Parotid Chronic Sclerosing Sialadenitis in an African-American Female: A Rare Case and Review of the Literature.
| Autor: | Keidar E; Otolaryngology - Head and Neck Surgery, McLaren Oakland Hospital, Pontiac, USA.; Medical Education, Michigan State University, East Lansing, USA., Shermetaro J; Medical Education, Michigan State University, East Lansing, USA., Kwartowitz G; Otolaryngology - Head and Neck Surgery, McLaren Oakland Hospital, Pontiac, USA. |
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| Jazyk: | angličtina |
| Zdroj: | Cureus [Cureus] 2020 Jun 26; Vol. 12 (6), pp. e8846. Date of Electronic Publication: 2020 Jun 26. |
| DOI: | 10.7759/cureus.8846 |
| Abstrakt: | Chronic sclerosing sialadenitis (CSS) or Küttner tumor is an under-recognized, benign fibroinflammatory disease most commonly seen in the submandibular gland of older adult males. Sialolithiasis or bacterial infection was first suspected as an etiology, but CSS is now considered an immunoglobulin G4-related disease (IgG4-RD). IgG4-RD can affect almost every organ in the body, characterized by organ fibrosis with IgG4-positive plasmacytes. Numerous autoimmune-related diseases have been unified under IgG4-RD, including Mikulicz disease (MD), autoimmune pancreatitis, Reidel's thyroiditis, and others. In any organ, IgG4-RD can present similar to malignancy. Due to the ability to mimic malignancy, it is crucial to be aware of this under-recognized clinical entity. CSS is currently of broad and high clinical interest due to increased understanding, multiorgan involvement, and more clearly defined criteria. To increase awareness of this disease, we describe a rare presentation of CSS with a literature review. Competing Interests: The authors have declared that no competing interests exist. (Copyright © 2020, Keidar et al.) |
| Databáze: | MEDLINE |
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