Effects of Parenteral Supplementation with Minerals and Vitamins on Oxidative Stress and Humoral Immune Response of Weaning Calves.

Autor: Mattioli GA; Laboratorio de Nutrición Mineral, Facultad de Ciencias Veterinarias, Universidad Nacional de La Plata, calle 60 y 118 s/n, 1900 La Plata, Buenos Aires, Argentina., Rosa DE; Laboratorio de Nutrición Mineral, Facultad de Ciencias Veterinarias, Universidad Nacional de La Plata, calle 60 y 118 s/n, 1900 La Plata, Buenos Aires, Argentina., Turic E; Biogenésis Bagó, Panamericana Km 38,5, B1619 Garín, Buenos Aires, Argentina., Picco SJ; Laboratorio de Nutrición Mineral, Facultad de Ciencias Veterinarias, Universidad Nacional de La Plata, calle 60 y 118 s/n, 1900 La Plata, Buenos Aires, Argentina., Raggio SJ; Biogenésis Bagó, Panamericana Km 38,5, B1619 Garín, Buenos Aires, Argentina., Minervino AHH; Laboratory of Animal Health, LARSANA, Federal University of Western Pará, UFOPA, Rua Vera Paz, s/n, 68040-255 Santarém, Pará, Brazil., Fazzio LE; Laboratorio de Nutrición Mineral, Facultad de Ciencias Veterinarias, Universidad Nacional de La Plata, calle 60 y 118 s/n, 1900 La Plata, Buenos Aires, Argentina.; LAPEVET-Laboratorio de Patología Especial Veterinaria (FCV-UNLP), Facultad de Ciencias Veterinarias, Universidad Nacional de La Plata, calle 60 y 118 s/n, 1900 La Plata, Argentina.
Jazyk: angličtina
Zdroj: Animals : an open access journal from MDPI [Animals (Basel)] 2020 Jul 29; Vol. 10 (8). Date of Electronic Publication: 2020 Jul 29.
DOI: 10.3390/ani10081298
Abstrakt: We aimed to evaluate the effects of injectable mineral and vitamin supplementation on weaning calves subjected to a low-stress (fence-line) weaning system. Seven-month-old Aberdeen Angus female calves (n = 40, 152 ± 11 kg body weight) from a selenium-deficient area of extensive cattle production on natural grass were randomly assigned to two groups (n = 20 each). One group received subcutaneous supplementation with copper, zinc, selenium, manganese and vitamins A and E (SG), and the other was given sterile saline solution (CG). The animals were supplemented twice, seven days before weaning (day -7) and on the day of weaning (day 0), and they were evaluated 30 (+30) and 60 (+60) days after weaning. Total antioxidant status (TAS), selenium-dependent glutathione peroxidase (GPx) activity, body weight, and average daily gain (ADG) were evaluated. Additionally, antibody titers were assessed prior to and after each immunization with a vaccine containing bovine herpes virus type 1 (BoHV-1). On day +30, body weight ( p = 0.03) was higher in SG, whereas TAS ( p = 0.02) and GPx ( p = 0.0038) activity were lower in CG and remained constant in SG. Antibody titers increased in SG and CG following immunization, being higher in SG on days +30 and +60 ( p < 0.05). In conclusion, parenteral supplementation of minerals and vitamins with antioxidant effects in a low-stress weaning system prevented the decrease in TAS and GPx activity, improved antibody response and had positive effects on body weight.
Databáze: MEDLINE