Increased Risk of Hospitalization and Death in Patients with COVID-19 and Pre-existing Noncommunicable Diseases and Modifiable Risk Factors in Mexico.

Autor: Hernández-Galdamez DR; INCAP Research Center for the Prevention of Chronic Diseases, Institute of Nutrition of Central America and Panama, Guatemala City, Guatemala., González-Block MÁ; Universidad Anáhuac México, Instituto Nacional de Salud Pública, Evisys Consulting, Ciudad de México, México., Romo-Dueñas DK; Red Nacional de Registros de Cáncer, Guanajuato, México, Instituto de Salud Pública del Estado de Guanajuato, Unidad de Vigilancia Epidemiologica Hospitalaria, Hospital General León, Guanajuato, México., Lima-Morales R; Secretaría de Salud de Tlaxcala, Dirección General, Tlaxcala, México., Hernández-Vicente IA; Secretaría de Salud de Tlaxcala, Hospital General de Huamantla, Tlaxcala, México; Universidad Autónoma de Tlaxcala, Facultad de Ciencias de la Salud, Tlaxcala, México., Lumbreras-Guzmán M; Universidad Autónoma de Tlaxcala, Facultad de Ciencias de la Salud, Tlaxcala, México; Secretaría de Salud de Tlaxcala, Centro de Salud Urbano de Villa Vicente Guerrero, Tlaxcala, México., Méndez-Hernández P; Universidad Autónoma de Tlaxcala, Facultad de Ciencias de la Salud, Tlaxcala, México; Secretaría de Salud de Tlaxcala, Departamento de Calidad y Educación en Salud, Tlaxcala, México. Electronic address: pmendezh@hotmail.com.
Jazyk: angličtina
Zdroj: Archives of medical research [Arch Med Res] 2020 Oct; Vol. 51 (7), pp. 683-689. Date of Electronic Publication: 2020 Jul 22.
DOI: 10.1016/j.arcmed.2020.07.003
Abstrakt: Background: The population in Mexico has high prevalence rates of noncommunicable diseases (NCDs). Hospitalization and death of COVID-19 patients in the countries most affected by the pandemic has been associated to chronic comorbidities.
Objective: To describe the prevalence of NCDs in patients with COVID-19 in Mexico and analyze the increased risk due to comorbidities and risk factors on hospitalization, utilization of intensive care units and death.
Methods: A cross-sectional study was performed from 212,802 confirmed COVID-19 cases reported by the Ministry of Health up to June 27, 2020. Odds ratios were performed using logistic regression model.
Results: Up to 47.40% of patients with COVID-19 diagnosis were also reported with a comorbidity, with hypertension being the most frequent (20.12%). The report of at least one NCD significantly increased the risk of death with respect to patients without such diagnoses. Chronic kidney disease increased the risk of death the most (OR 2.31), followed by diabetes (OR 1.69), immunosuppression (OR 1.62), obesity (OR 1.42), hypertension (OR 1.24), chronic obstructive pulmonary disease (OR 1.20). The comorbidities that most increased the risk of ICU and of intubation were diabetes, immunosuppression and obesity.
Conclusion: NCD comorbidities increase the severity of COVID-19 infection. Given high NCD prevalence rates among the Mexican population, the pandemic poses a special threat to the health system and to society. Special prevention measures need to be strengthened for persons with NCD diagnoses in the short-term. In the mid-term, disease control strategies need to be improved to protect these patients against COVID-19 severity.
(Copyright © 2020 IMSS. Published by Elsevier Inc. All rights reserved.)
Databáze: MEDLINE
Externí odkaz: