| Autor: |
Nooromid MJ; Division of Vascular Surgery, 24560Northwestern University Feinberg School of Medicine, Chicago, IL, USA., Thomas MA; Division of Vascular Surgery, 24560Northwestern University Feinberg School of Medicine, Chicago, IL, USA., Yoon DY; Division of Vascular Surgery, 24560Northwestern University Feinberg School of Medicine, Chicago, IL, USA., Eskandari MK; Division of Vascular Surgery, 24560Northwestern University Feinberg School of Medicine, Chicago, IL, USA., Peabody TD; Department of Orthopedic Surgery, 24560Northwestern University Feinberg School of Medicine, Chicago, IL, USA., Rodriguez HE; Division of Vascular Surgery, 24560Northwestern University Feinberg School of Medicine, Chicago, IL, USA. |
| Jazyk: |
angličtina |
| Zdroj: |
Vascular and endovascular surgery [Vasc Endovascular Surg] 2020 Oct; Vol. 54 (7), pp. 579-585. Date of Electronic Publication: 2020 Aug 03. |
| DOI: |
10.1177/1538574420942334 |
| Abstrakt: |
Objective : To describe the types of intervention and determine patency and survival after arterial and venous reconstruction after surgical excision of sarcomas. Methods : Between November 2001 and July 2015, 42 patients with sarcomas and vascular involvement underwent surgical oncologic resection followed by arterial or venous reconstruction or preservation of the native vascular bundle. Univariate, multivariate, and Kaplan-Meier survival analyses were performed on abstracted data, which included demographics, risk factors, oncologic and vascular treatment modalities, postoperative complications, graft patency, and survival outcomes. Results : A total of 42 sarcomas required vascular assistance for oncologic removal. The majority of sarcomas were malignant fibrous histiocytoma (23.8%), and the most common anatomic location was the retroperitoneum (48%). A total of 12 revascularizations procedures were performed, including 5 arterial, 3 venous, and 2 concomitant arterial and venous. In 32 cases, a vascular surgeon was needed for vessel ligation, repair, or mobilization. The overall 2- and 5-year survival was 77.7% and 26.2%, respectively, with no significant survival difference between patients who underwent revascularization compared to those without revascularization. There was a 100% patency rate in all cases at last follow-up, regardless of the type of vascular reconstruction (median 18 months, range 1-29 months). On multivariate analysis, chronic obstructive pulmonary disease (COPD; P = .002) and positive surgical margins ( P = .003) were associated with decreased survival. Most cases were performed in the last 5 years of the study (n = 27, 64.3%). Conclusions : Vascular reconstruction is feasible after surgical oncologic resection of sarcomas with good mid-term patency and limb preservation. Factors independently associated with mortality included COPD and positive surgical margins. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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