A Rare Case of Vulvar Superficial Angiomyxoma in a Pediatric Patient.

Autor: O'Flynn O'Brien KL; Division of Pediatric and Adolescent Gynecology, Department of Obstetrics and Gynecology, Baylor College of Medicine, Houston, Texas. Electronic address: kofob10@gmail.com., Cortes-Santiago N; Department of Pathology and Immunology, Baylor College of Medicine and Department of Pathology, Texas Children's Hospital, Houston, Texas., Patil NM; Department of Pathology and Immunology, Baylor College of Medicine and Department of Pathology, Texas Children's Hospital, Houston, Texas., Bercaw-Pratt JL; Division of Pediatric and Adolescent Gynecology, Department of Obstetrics and Gynecology, Baylor College of Medicine, Houston, Texas.
Jazyk: angličtina
Zdroj: Journal of pediatric and adolescent gynecology [J Pediatr Adolesc Gynecol] 2020 Dec; Vol. 33 (6), pp. 727-729. Date of Electronic Publication: 2020 Jul 30.
DOI: 10.1016/j.jpag.2020.07.015
Abstrakt: Background: Superficial angiomyxoma (SAM) is a rare, benign cutaneous tumor. Originally described as a component of Carney complex, it is now recognized as a sporadic condition.
Case: A 7-year-old girl was referred for management of a 2.5-cm mass arising from the right labia majora. Key pathologic features included lobules of spindle-shaped cells in a myxoid matrix and prominent neutrophilic infiltrate. The cells were positive for CD34 and negative for desmin, progesterone receptor, and estrogen receptor staining.
Summary and Conclusion: This case is that of the youngest described patient with vulvar SAM. Patients should be carefully examined for manifestations of Carney complex to avoid potentially life-threatening complications. It is critical to distinguish SAM from aggressive angiomyxoma. The patient was referred to genetics and will be followed for local recurrence.
(Copyright © 2020 North American Society for Pediatric and Adolescent Gynecology. Published by Elsevier Inc. All rights reserved.)
Databáze: MEDLINE
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