The First 100 Days of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Control in Vietnam.

Autor:	Thai PQ; National Institute of Hygiene and Epidemiology, Hanoi, Vietnam.; School of Preventive Medicine and Public Health, Hanoi Medical University, Hanoi, Vietnam., Rabaa MA; Centre for Tropical Medicine and Global Health, Nuffield Department of Medicine, University of Oxford, Oxford, United Kingdom.; Oxford University Clinical Research Unit, Ho Chi Minh city, Vietnam., Luong DH; Medical Services Administration, Ministry of Health, Hanoi, Vietnam., Tan DQ; General Department of Preventive Medicine, Ministry of Health, Hanoi, Vietnam., Quang TD; General Department of Preventive Medicine, Ministry of Health, Hanoi, Vietnam., Quach HL; National Institute of Hygiene and Epidemiology, Hanoi, Vietnam.; Research School of Population Health, Australian National University, Canberra, Australia., Hoang Thi NA; National Institute of Hygiene and Epidemiology, Hanoi, Vietnam.; Research School of Population Health, Australian National University, Canberra, Australia., Dinh PC; National Agency for Science and Technology Information, Ministry of Science and Technology, Hanoi, Vietnam., Nghia ND; National Institute of Hygiene and Epidemiology, Hanoi, Vietnam., Tu TA; National Institute of Hygiene and Epidemiology, Hanoi, Vietnam., Quang N; Hanoi University of Public Health, Hanoi, Vietnam., Phuc TM; Oxford University Clinical Research Unit, Ho Chi Minh city, Vietnam., Chau V; Oxford University Clinical Research Unit, Ho Chi Minh city, Vietnam., Khanh NC; National Institute of Hygiene and Epidemiology, Hanoi, Vietnam., Anh DD; National Institute of Hygiene and Epidemiology, Hanoi, Vietnam., Duong TN; National Institute of Hygiene and Epidemiology, Hanoi, Vietnam., Thwaites G; Centre for Tropical Medicine and Global Health, Nuffield Department of Medicine, University of Oxford, Oxford, United Kingdom.; Oxford University Clinical Research Unit, Ho Chi Minh city, Vietnam., van Doorn HR; Centre for Tropical Medicine and Global Health, Nuffield Department of Medicine, University of Oxford, Oxford, United Kingdom.; Oxford University Clinical Research Unit, Ho Chi Minh city, Vietnam., Choisy M; Centre for Tropical Medicine and Global Health, Nuffield Department of Medicine, University of Oxford, Oxford, United Kingdom.; Oxford University Clinical Research Unit, Ho Chi Minh city, Vietnam.
Jazyk:	angličtina
Zdroj:	Clinical infectious diseases : an official publication of the Infectious Diseases Society of America [Clin Infect Dis] 2021 May 04; Vol. 72 (9), pp. e334-e342.
DOI:	10.1093/cid/ciaa1130
Abstrakt:	Background: One hundred days after severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) was first reported in Vietnam on 23 January, 270 cases were confirmed, with no deaths. We describe the control measures used by the government and their relationship with imported and domestically acquired case numbers, with the aim of identifying the measures associated with successful SARS-CoV-2 control. Methods: Clinical and demographic data on the first 270 SARS-CoV-2 infected cases and the timing and nature of government control measures, including numbers of tests and quarantined individuals, were analyzed. Apple and Google mobility data provided proxies for population movement. Serial intervals were calculated from 33 infector-infectee pairs and used to estimate the proportion of presymptomatic transmission events and time-varying reproduction numbers. Results: A national lockdown was implemented between 1 and 22 April. Around 200 000 people were quarantined and 266 122 reverse transcription polymerase chain reaction (RT-PCR) tests conducted. Population mobility decreased progressively before lockdown. In total, 60% (163/270) of cases were imported; 43% (89/208) of resolved infections remained asymptomatic for the duration of infection. The serial interval was 3.24 days, and 27.5% (95% confidence interval [CI], 15.7%-40.0%) of transmissions occurred presymptomatically. Limited transmission amounted to a maximum reproduction number of 1.15 (95% CI, .·37-2.·36). No community transmission has been detected since 15 April. Conclusions: Vietnam has controlled SARS-CoV-2 spread through the early introduction of mass communication, meticulous contact tracing with strict quarantine, and international travel restrictions. The value of these interventions is supported by the high proportion of asymptomatic and imported cases, and evidence for substantial presymptomatic transmission. (© The Author(s) 2020. Published by Oxford University Press for the Infectious Diseases Society of America.)
Databáze:	MEDLINE
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