[Seroprevalence of anti-Mycoplasma pneumoniae antibodies in otherwise healthy children].

Autor: Sanluis Fenelli G; Hospital General de Niños Pedro de Elizalde, Buenos Aires, Argentina., Chiolo MJ; Departamento de cirugía, Hospital General de Niños Pedro de Elizalde, Buenos Aires, Argentina., Torres FA; Hospital General de Niños Pedro de Elizalde, Buenos Aires, Argentina., Balbaryski J; División Inmunología, Hospital General de Niños Pedro de Elizalde, Buenos Aires, Argentina., Domínguez P; Hospital General de Niños Pedro de Elizalde, Buenos Aires, Argentina., Ossorio MF; Hospital General de Niños Pedro de Elizalde, Buenos Aires, Argentina., Rial MJ; División Laboratorio central, Hospital General de Niños Pedro de Elizalde, Buenos Aires, Argentina., Ferrero F; Departamento de Medicina, Hospital General de Niños Pedro de Elizalde, Buenos Aires, Argentina.
Jazyk: Spanish; Castilian
Zdroj: Revista chilena de pediatria [Rev Chil Pediatr] 2020 Jun; Vol. 91 (3), pp. 347-352.
DOI: 10.32641/rchped.v91i3.1476
Abstrakt: Introduction: Mycoplasma pneumoniae (Mypn) infection could be occurring at an earlier age due to social pheno mena such as attending daycare centers more frequently and earlier than decades ago.
Objective: to estimate the prevalence of anti-Mypn antibodies in children aged 0-12 years, and to explore whether age, attendance to daycare center/school, overcrowding or the presence of children aged below 12 years in the households increase the risk of seropositivity.
Patients and Method: Cross-sectional stu dy including healthy children aged 0-12 years which required blood draws for routine laboratory tests. In all cases, the aforementioned variables were recorded and anti-Mypn IgG was determined by enzyme immunoassay. The association between predictors and seropositivity was assessed in a logistic regression model.
Results: We included 232 patients (average age 56.4 ± 40.0 months). 56.9% attended a daycare center/school, 63.8% co-habited with children under 12 years old, and 15.9% lived in overcrowded households. The prevalence of anti-Mypn antibodies was 14.6%. There were no significant differences between seropositive and seronegative children regarding age (63.1 ± 40.7 vs. 55.4 ± 41.3 months), school/day-care attendance (64.7% vs. 55.5%), overcrowding (14.7% vs. 14.9%), or co-habiting with children (64.7% vs. 63.6%). Age was not an independent predictor of seropositivity in the multivariate model.
Conclusion: The prevalence of anti-Mypn antibodies in children was 14.6% and age was not a predictor of seropositivity.
Databáze: MEDLINE