Diagnosis of primary osteosarcoma of the urinary bladder in a resource-limited setting: a case report and review of the literature.

Autor:	Mremi A; Department of Pathology, Kilimanjaro Christian Medical Centre (KCMC), Moshi, Tanzania., Pyuza JJ; Department of Pathology, Kilimanjaro Christian Medical Centre (KCMC), Moshi, Tanzania., Bartholomeo N; Department of Urology, Kilimanjaro Christian Medical Centre (KCMC), Moshi, Tanzania., Andongolile AA; Kilimanjaro Clinical Research Institute (KCRI), Kilimanjaro Christian Medical Centre (KCMC), Moshi, Tanzania., Yahaya JJ; Department of Biomedical Science, College of Health Sciences (CHS), The University of Dodoma, Dodoma, Tanzania.
Jazyk:	angličtina
Zdroj:	Journal of surgical case reports [J Surg Case Rep] 2020 Jul 23; Vol. 2020 (7), pp. rjaa236. Date of Electronic Publication: 2020 Jul 23 (Print Publication: 2020).
DOI:	10.1093/jscr/rjaa236
Abstrakt:	Extraskeletal osteosarcoma is a rare malignant mesenchymal soft tissue tumor without attachment to the bone and is able to produce osteoid or cartilaginous matrix. Rendering a definitive diagnosis may pose a challenge particularly in a resource-limited setting. We report a case of primary osteosarcoma of the urinary bladder presenting with hematuria, dysuria and positive history of schistosomal contact. Computed tomography intravenous urogram revealed a large heterogeneous mass at the right superolateral aspect of the urinary bladder. Morphological evaluation of the biopsy and a minimal panel of immunohistochemical antibodies of vimentin and cytokeratin 20 ruled out potential differentials and thus confirmed the diagnosis of osteosarcoma. (Published by Oxford University Press and JSCR Publishing Ltd. All rights reserved. © The Author(s) 2020.)
Databáze:	MEDLINE
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