Disseminated fusariosis in a patient with bone marrow aplasia.

Autor: Chagas DF; Dermatology Service, Hospital Universitário Cassiano Antonio Moraes, Universidade Federal do Espírito Santo, Vitória, ES, Brazil. Electronic address: daaani__@hotmail.com., Diniz LM; Dermatology Service, Hospital Universitário Cassiano Antonio Moraes, Universidade Federal do Espírito Santo, Vitória, ES, Brazil., Lucas EA; Dermatology Service, Hospital Universitário Cassiano Antonio Moraes, Universidade Federal do Espírito Santo, Vitória, ES, Brazil., Nogueira PSE; Dermatology Service, Hospital Universitário Cassiano Antonio Moraes, Universidade Federal do Espírito Santo, Vitória, ES, Brazil.
Jazyk: angličtina
Zdroj: Anais brasileiros de dermatologia [An Bras Dermatol] 2020 Sep - Oct; Vol. 95 (5), pp. 609-614. Date of Electronic Publication: 2020 Jul 04.
DOI: 10.1016/j.abd.2019.12.008
Abstrakt: Fusariosis is a superficial or systemic infection, which occurs mainly in immunocompromised hosts, especially in patients with hematological neoplasia; 70%-75% of the cases present cutaneous manifestations. The disseminated form is rare and difficult to diagnose; even with specific treatment, the evolution is usually fatal. Currently, it is considered an emerging disease; in some centers, it is the second most common cause of invasive mycosis, after aspergillosis. The authors describe a case of a female patient with idiopathic bone marrow aplasia and disseminated fusariosis, who initially appeared to benefit from voriconazole and amphotericin B; however, due to persistent neutropenia, her clinical condition deteriorated with fatal evolution.
(Copyright © 2020 Sociedade Brasileira de Dermatologia. Published by Elsevier España, S.L.U. All rights reserved.)
Databáze: MEDLINE