Performance of Ultrasonography Compared to Conventional Radiography for the Diagnosis of Osteoarthritis in Patients With Knee Pain.

Autor:	Brom M; Rheumatology Department, Hospital Italiano de Buenos Aires, Buenos Aires, Argentina., Gandino IJ; Rheumatology Department, Hospital Italiano de Buenos Aires, Buenos Aires, Argentina., Zacariaz Hereter JB; Rheumatology Department, Hospital Italiano de Buenos Aires, Buenos Aires, Argentina., Scolnik M; Rheumatology Department, Hospital Italiano de Buenos Aires, Buenos Aires, Argentina., Mollerach FB; Rheumatology Department, Hospital Italiano de Buenos Aires, Buenos Aires, Argentina., Ferreyra Garrott LG; Rheumatology Department, Hospital Italiano de Buenos Aires, Buenos Aires, Argentina., Marin J; Rheumatology Department, Hospital Italiano de Buenos Aires, Buenos Aires, Argentina., Ruta SO; Rheumatology Department, Hospital Italiano de Buenos Aires, Buenos Aires, Argentina., Rosa JE; Rheumatology Department, Hospital Italiano de Buenos Aires, Buenos Aires, Argentina., García-Mónaco RD; Radiology Department, Hospital Italiano de Buenos Aires, Buenos Aires, Argentina., Soriano ER; Rheumatology Department, Hospital Italiano de Buenos Aires, Buenos Aires, Argentina.
Jazyk:	angličtina
Zdroj:	Frontiers in medicine [Front Med (Lausanne)] 2020 Jul 03; Vol. 7, pp. 319. Date of Electronic Publication: 2020 Jul 03 (Print Publication: 2020).
DOI:	10.3389/fmed.2020.00319
Abstrakt:	Purpose: To investigate the performance of ultrasonography (US) for the detection of knee osteoarthritis (OA) in patients suffering from knee pain, compared to conventional radiographs. Methods: Cross-sectional study performed at a university teaching hospital. Consecutive patients complaining of unilateral or bilateral mechanical knee pain who signed an informed consent were included. All patients underwent simultaneously an ultrasonographic and a radiographic evaluation of the knee. Exclusion criteria were age under 18 years, prior diagnosis of knee OA, diagnosis of inflammatory arthritis, history of knee surgery or trauma, severe knee deformities, and corticosteroid injection within the last 2 months. The diagnostic properties of US for the detection of knee OA were evaluated using radiological data as the reference method. Evaluated test properties were sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV), and the positive and negative likelihood ratio (LR+ and LR-). Results: Three-hundred twenty-two knees (281 patients) were included. Radiographic degenerative changes were present in 56.8% (183) of the evaluated knees. Regarding the diagnostic properties of the US, the presence of either osteophytes or the compromise of the femoral hyaline cartilage had the best sensitivity to detect OA (95%), with a NPV of 92% and a LR- of 0,07, while the combined identification of osteophytes and compromise of the femoral hyaline cartilage had the best specificity (94%), with 94% PPV and a LR+ of 13. Conclusion: US demonstrated an excellent sensitivity with an adequate specificity for the detection of radiographic knee OA. (Copyright © 2020 Brom, Gandino, Zacariaz Hereter, Scolnik, Mollerach, Ferreyra Garrott, Marin, Ruta, Rosa, García-Mónaco and Soriano.)
Databáze:	MEDLINE
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