A review of toxic effects of electronic cigarettes/vaping in adolescents and young adults.

Autor: Overbeek DL; Harvard Medical Toxicology, Boston Children's Hospital, Boston, MA, USA.; Department of Emergency Medicine, Brigham and Women's Hospital, Boston, MA, USA., Kass AP; Department of Pulmonary Medicine, Boston Children's Hospital, Boston, MA, USA., Chiel LE; Department of Pulmonary Medicine, Boston Children's Hospital, Boston, MA, USA., Boyer EW; Department of Emergency Medicine, Brigham and Women's Hospital, Boston, MA, USA., Casey AMH; Department of Pulmonary Medicine, Boston Children's Hospital, Boston, MA, USA.
Jazyk: angličtina
Zdroj: Critical reviews in toxicology [Crit Rev Toxicol] 2020 Jul; Vol. 50 (6), pp. 531-538. Date of Electronic Publication: 2020 Jul 27.
DOI: 10.1080/10408444.2020.1794443
Abstrakt: In this review, we examine the known and suspected toxicity of electronic cigarettes (e-cigarettes) in adolescents and young adults, to improve awareness of risks and identification of complications of their use. The use of e-cigarettes, or "vaping," is exploding among the pediatric population. E-cigarettes heat a solution containing a psychoactive compound, most commonly nicotine or tetrahydrocannabinol (THC), along with flavorings and other additives to a vapor, which users inhale. Since their introduction in the early 2000s, e-cigarette use is now prolific among youth, per the Monitoring the Future survey, with over 40% of high school seniors reporting use within the past year. Adolescents are vulnerable to the risks of e-cigarettes, as they are targeted as new consumers with advertisements and flavoring compounds, and are not utilizing them as a means to smoking cessation. The pulmonary risks of vaping are rapidly emerging, with the most immediately alarming being the condition electronic-cigarette/vaping associated lung injury (EVALI). Additionally, there have been more recent studies showing extrapulmonary effects including cardiovascular, immunologic and neuro-developmental effects. Many of these effects are likely dose-dependent. Public health efforts are urgently needed to decrease or eliminate new e-cigarette initiation, and support should be established to assist current e-cigarette users with cessation. We strongly advocate for the elimination of e-cigarette flavorings and advertising directed at adolescents, and call for physicians to be cognizant of this expanding epidemic.
Databáze: MEDLINE
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