Maintenance of sexual activity following androgen deprivation in males.

Autor: Duthie CJ; Department of Anatomy, University of Otago, 270 Great King St, Dunedin, 9016, New Zealand. Electronic address: dutca717@student.otago.ac.nz., Calich HJ; Ocean Graduate School, University of Western Australia. 35 Stirling Highway, Perth, Western Australia, 6009 Australia. Electronic address: hannah.calich@research.uwa.edu.au., Rapsey CM; Department of Psychological Medicine, University of Otago, 464 Cumberland St, 9054, New Zealand. Electronic address: charlene.rapsey@otago.ac.nz., Wibowo E; Department of Anatomy, University of Otago, 270 Great King St, Dunedin, 9016, New Zealand. Electronic address: erik.wibowo@otago.ac.nz.
Jazyk: angličtina
Zdroj: Critical reviews in oncology/hematology [Crit Rev Oncol Hematol] 2020 Sep; Vol. 153, pp. 103064. Date of Electronic Publication: 2020 Jul 15.
DOI: 10.1016/j.critrevonc.2020.103064
Abstrakt: Androgen deprivation therapy (ADT) is a common treatment for men with systemic prostate cancer. However, ADT leads to sexual dysfunction, causing >80 % of couples to cease sexual activity completely. Here, we use a biopsychosocial framework to review factors that may influence the ability of patients on ADT to remain sexually active. We address sexual factors prior to ADT, neurobiological factors, intermittent ADT, sex aids, exercise, sleep, partner factors, masculinity, non-penetrative intimacy, depressive symptoms, and access to counselling or patient education programs. We make suggestions for future research in order to extend our understanding in this field with the goal of improving evidence-based treatment protocols and practice. Importantly, we suggest that clinicians should discuss options for sexual intimacy after ADT with both patients and their partners, as sexual inactivity is not inevitable for most, and strategies are available for helping maintain sexual intimacy.
(Copyright © 2020 Elsevier B.V. All rights reserved.)
Databáze: MEDLINE
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