Mass-forming pancreatitis versus pancreatic ductal adenocarcinoma: CT and MR imaging for differentiation.

Autor: Schima W; Department of Diagnostic and Interventional Radiology, Goettlicher Heiland Krankenhaus, Barmherzige Schwestern Krankenhaus, 1170 Wien, Dornbacher Strasse 20-30, St. Josef-Krankenhaus, Vienna, Austria. wolfgang.schima@khgh.at., Böhm G; Department of Radiology, Ordensklinikum, Linz, Austria., Rösch CS; Department of Surgery, Ordensklinikum, Linz, Austria., Klaus A; Department of Surgery, Barmherzige Schwestern Krankenhaus, Vienna, Austria., Függer R; Department of Surgery, Ordensklinikum, Linz, Austria., Kopf H; Department of Diagnostic and Interventional Radiology, Goettlicher Heiland Krankenhaus, Barmherzige Schwestern Krankenhaus, 1170 Wien, Dornbacher Strasse 20-30, St. Josef-Krankenhaus, Vienna, Austria.
Jazyk: angličtina
Zdroj: Cancer imaging : the official publication of the International Cancer Imaging Society [Cancer Imaging] 2020 Jul 23; Vol. 20 (1), pp. 52. Date of Electronic Publication: 2020 Jul 23.
DOI: 10.1186/s40644-020-00324-z
Abstrakt: Various inflammatory abnormalities of the pancreas can mimic pancreatic ductal adenocarcinoma (PDAC) at cross-sectional imaging. Misdiagnosis of PDAC at imaging may lead to unnecessary surgery. On the other hand, chronic pancreatitis (CP) bears a greater risk of developing PDAC during the course of the disease. Thus, differentiation between mass-forming chronic pancreatitis (MFCP) and PDAC is important to avoid unnecessary surgery and not to delay surgery of synchronous PDAC in CP.Imaging features such as the morphology of the mass including displacement of calcifications, presence of duct penetrating, sign appearance of duct stricturing, presence or absence of vessel encasement, apparent diffusion coefficient (ADC) value and intravoxel incoherent motion (IVIM) at diffusion-weighted imaging (DWI), fluorodeoxyglucose (FDG) uptake in PET/CT, and mass perfusion parameters can help to differentiate between PDAC and MFCP. Correct interpretation of imaging features can appropriately guide biopsy and surgery, if necessary. This review summarizes the relevant computed tomography (CT) and magnetic resonance imaging (MRI) features that can help the radiologist to come to a confident diagnosis and to guide further management in equivocal cases.
Databáze: MEDLINE