Practice Patterns for Eosinophilic Esophagitis Patients in Busan and Gyeongnam: A Korean Multicenter Database Study.

Autor: Kim SJ; Department of Internal Medicine, Pusan National University School of Medicine, and Biomedical Research Institute, Pusan National University Yangsan Hospital, Yangsan, Gyeongsangnam-do, Korea., Park MI; Department of Internal Medicine, Kosin University College of Medicine, Busan, Korea., Kim GH; Department of Internal Medicine, Pusan National University School of Medicine, and Biomedical Research Institute, Pusan National University Hospital, Busan, Korea., Lee MW; Department of Internal Medicine, Pusan National University School of Medicine, and Biomedical Research Institute, Pusan National University Hospital, Busan, Korea., Jung K; Department of Internal Medicine, Kosin University College of Medicine, Busan, Korea., Lee J; Department of Internal Medicine, Inje University College of Medicine, Haeundae Paik Hospital, Busan, Korea., Seol SY; Department of Internal Medicine, Inje University College of Medicine, Busan Paik Hospital, Busan, Korea., Jee SR; Department of Internal Medicine, Inje University College of Medicine, Busan Paik Hospital, Busan, Korea., Lee HS; Department of Internal Medicine, Inje University College of Medicine, Busan Paik Hospital, Busan, Korea., Jang JS; Department of Internal Medicine, Dong-A University Hospital, Busan, Korea., Cha JH; Department of Internal Medicine, Dong-A University Hospital, Busan, Korea.
Jazyk: angličtina
Zdroj: Journal of neurogastroenterology and motility [J Neurogastroenterol Motil] 2021 Jan 30; Vol. 27 (1), pp. 71-77.
DOI: 10.5056/jnm20069
Abstrakt: Background/aims: The prevalence of eosinophilic esophagitis is increasing in Korea and there are few single-center studies regarding eosinophilic esophagitis in Korea. In particular, data about management for eosinophilic esophagitis are lacking. We aim to evaluate the practice patterns, including initial treatment and response, in the Busan city and Gyeongnam province area.
Methods: We retrospectively reviewed medical records to gain data on patient characteristics, medication, endoscopic images, and esophageal biopsy results. From January 2009 to December 2019, a total of 42 patients were diagnosed with eosinophilic esophagitis.
Results: The mean age was 50.7 (from 22 to 81) years and the cohort was predominantly male (78.6%, 33/42). The proton pump inhibitor was the preferred treatment as an initial trial for 64.3% (27/42) of patients, followed by swallowed topical steroids (16.7%, 7/42). Clinical improvement after proton pump inhibitor therapy was achieved in 88.9% (24/27) of patients. Two patients who did not achieve improvement showed a clinical and endoscopic response after swallowed topical steroids treatment. No patient received diet elimination or balloon dilatation therapy.
Conclusions: The treatment response of eosinophilic esophagitis was good in Busan city and Gyeongnam province area in Korea. Proton pump inhibitor therapy was the preferred and most effective treatment for eosinophilic esophagitis as the initial therapy.
Databáze: MEDLINE
Externí odkaz: