Elevated serum β -d- glucan levels in cavitary pulmonary nocardiosis.

Autor:	Yagyu K; Department of Respiratory Medicine, Izumi City General Hospital, Izumi, Osaka, Japan yagyu604@helen.ocn.ne.jp., Nakatsuji Y; Department of Respiratory Medicine, Izumi City General Hospital, Izumi, Osaka, Japan., Matsushita H; Department of Respiratory Medicine, Izumi City General Hospital, Izumi, Osaka, Japan.
Jazyk:	angličtina
Zdroj:	BMJ case reports [BMJ Case Rep] 2020 Jul 22; Vol. 13 (7). Date of Electronic Publication: 2020 Jul 22.
DOI:	10.1136/bcr-2020-234738
Abstrakt:	An 86-year-old woman with Borrmann type III colorectal cancer (Union for International Cancer Control pT4aN2bM1c, pStage IVc) had received dexamethasone for the last 6 months as palliative care. She presented with a low-grade fever, chest pain and cough. Chest radiography on admission showed cavities and consolidations bilaterally in the upper lobes. A blood examination on admission revealed highly elevated serum β-d-glucan levels. The diagnosis by bronchoscopy was pulmonary nocardiosis. With trimethoprim/sulfamethoxazole and imipenem/cilastatin, the β-d-glucan levels were decreased, and chest X-ray showed improvement after 1 month. β-d-glucan is known to be a biomarker of fungal infection. It is possible that β-d-glucan levels also indicate a pulmonary infection by Nocardia . Competing Interests: Competing interests: None declared. (© BMJ Publishing Group Limited 2020. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ.)
Databáze:	MEDLINE
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