Preliminary survey of the attitudes of Brazilian scientists towards pain management and assessment in animals used in science.

Autor:	Tomacheuski RM; Department of Anesthesiology, Medical School (FMB) of São Paulo State University (UNESP), Botucatu, SP, Brazil. Electronic address: rubia_mitalli@hotmail.com., Taffarel MO; Department of Veterinary Medicine, Maringá State University (UEM), Umuarama, PR, Brazil., Ferrante M; Department of Veterinary Medicine, Federal University of Lavras (UFLA), Lavras, MG, Brazil., Luna SP; Department of Veterinary Surgery and Animal Reproduction, School of Veterinary Medicine and Animal Science, São Paulo State University (UNESP), Botucatu, SP, Brazil.
Jazyk:	angličtina
Zdroj:	Veterinary anaesthesia and analgesia [Vet Anaesth Analg] 2020 Sep; Vol. 47 (5), pp. 647-656. Date of Electronic Publication: 2020 Jun 10.
DOI:	10.1016/j.vaa.2020.05.007
Abstrakt:	Objective: To investigate the current scenario in Brazil regarding pain assessment and control in experimental animals. Study Design: Prospective survey. Methods: A confidential questionnaire was available online and sent by e-mail to Brazilian scientists working with animal experimentation in Brazil. Data collection was conducted from October 2016 to October 2017. The exclusion criteria included blank questionnaires or with <80% completed responses, researchers not performing experiments involving animals and foreign scientists. Results: A total of 96 questionnaires from 104 respondents were analyzed. The Fisher's exact test showed a disparity between the proportions of scientists who recognized the importance of analgesia and their application of analgesic techniques in painful procedures (p < 0.0003), and also for the researchers who assumed that experiments inflicted pain and their classification of the degree of invasiveness (p < 0.0001), indicating their insufficient knowledge of these topics. Overall, 77% of institutions did not offer specific training to assess pain in experimental animals, and 24% of respondents had no training to work with animal experimentation. In total, 62% of the studies inflicted pain, 48% of respondents used pain scales, and the drugs administered most frequently for pain management were morphine (44%), meloxicam (43%) and tramadol (37%); 15% of respondents did not include analgesics even though their studies inflicted pain. Commonly used animals were rats (33%), mice (29%) and rabbits (8%). Conclusions and Clinical Relevance: The results of this preliminary survey indicated that in Brazil there is a gap in the knowledge and training on pain assessment and management of experimental animals. Therefore, there is a necessity for an educational program to prepare and train scientists to assess and manage pain in laboratory or experimental animals. Further studies using a psychometrically validated survey instrument are warranted. (Copyright © 2020 Association of Veterinary Anaesthetists and American College of Veterinary Anesthesia and Analgesia. Published by Elsevier Ltd. All rights reserved.)
Databáze:	MEDLINE
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