Associations between particulate matter air pollution, presence and progression of subclinical coronary and carotid atherosclerosis: A systematic review.

Autor: Jilani MH; Department of Medicine, SUNY Upstate Medical University, Syracuse, NY, USA., Simon-Friedt B; Center for Health & Nature, Houston Methodist Research Institute, Houston, TX, USA; Center for Outcomes Research, Houston Methodist, Houston, TX, USA., Yahya T; Division of Cardiovascular Prevention and Wellness, Department of Cardiology, Houston Methodist DeBakey Heart & Vascular Center, Houston, TX, USA., Khan AY; Department of Medicine, St Joseph Mercy Oakland Hospital, Pontiac, MI, USA., Hassan SZ; Division of Cardiovascular Prevention and Wellness, Department of Cardiology, Houston Methodist DeBakey Heart & Vascular Center, Houston, TX, USA., Kash B; Center for Health & Nature, Houston Methodist Research Institute, Houston, TX, USA; Center for Outcomes Research, Houston Methodist, Houston, TX, USA; Texas A&M University School of Public Health, College Station, TX, USA., Blankstein R; Division of Cardiovascular Medicine, Department of Medicine, Brigham and Women's Hospital, Boston, MA, USA., Blaha MJ; Ciccarone Center for the Prevention of Cardiovascular Disease, Johns Hopkins University School of Medicine, Baltimore, MD, USA., Virani SS; Division of Cardiology, Department of Medicine, Baylor College of Medicine, Houston, TX, USA., Rajagopalan S; Harrington Heart and Vascular Institute, University Hospitals, Cleveland, OH, USA; Case Western Reserve University School of Medicine, Cleveland, OH, USA., Cainzos-Achirica M; Center for Health & Nature, Houston Methodist Research Institute, Houston, TX, USA; Center for Outcomes Research, Houston Methodist, Houston, TX, USA; Division of Cardiovascular Prevention and Wellness, Department of Cardiology, Houston Methodist DeBakey Heart & Vascular Center, Houston, TX, USA; Ciccarone Center for the Prevention of Cardiovascular Disease, Johns Hopkins University School of Medicine, Baltimore, MD, USA., Nasir K; Center for Health & Nature, Houston Methodist Research Institute, Houston, TX, USA; Center for Outcomes Research, Houston Methodist, Houston, TX, USA; Division of Cardiovascular Prevention and Wellness, Department of Cardiology, Houston Methodist DeBakey Heart & Vascular Center, Houston, TX, USA; Ciccarone Center for the Prevention of Cardiovascular Disease, Johns Hopkins University School of Medicine, Baltimore, MD, USA. Electronic address: knasir@houstonmethodist.org.
Jazyk: angličtina
Zdroj: Atherosclerosis [Atherosclerosis] 2020 Aug; Vol. 306, pp. 22-32. Date of Electronic Publication: 2020 Jul 05.
DOI: 10.1016/j.atherosclerosis.2020.06.018
Abstrakt: Background and Aims: Long-term exposure to particulate matter (PM) air pollution has been linked with increased cardiovascular events and mortality, however, studies had shown inconsistent associations between PM exposure and subclinical atherosclerosis.
Methods: We performed an updated systematic literature review to identify studies evaluating the associations between PM and subclinical atherosclerosis, measured using presence/progression of coronary artery calcium (CAC) or carotid intima-media thickness (CIMT) in adult populations. Quality was assessed using the Newcastle-Ottawa scale.
Results: Eighteen studies were included: 5 cohorts and 13 cross-sectional. Amongst 7 studies that evaluated the associations between PM and prevalence of CAC, 4 reported significantly higher odds of detectable CAC>0 or CAC>400 with increased PM exposure. Nine studies evaluated the association between exposure to at least one of the particulates and CIMT; of these, 6 reported significant independent associations. Two studies evaluated PM 2.5 and CAC progression, with 1 reporting a greater progression of CAC with increased exposure to PM, while 3 out of 4 studies evaluating CIMT progression showed no significant difference in CIMT progression with a higher PM 2.5 exposure. Additionally, 3 studies found significant associations between proximity to major roadways and measures of subclinical atherosclerosis. Among null studies, most displayed non-significant trends towards higher atherosclerosis burden with higher PM exposure.
Conclusions: Overall, available observational studies support a positive association between PM exposure and subclinical atherosclerosis. Further longitudinal studies are needed to better establish this relationship and assess the efficacy of previously identified interventions on mitigation of clinical cardiovascular disease.
(Copyright © 2020 Elsevier B.V. All rights reserved.)
Databáze: MEDLINE
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