Impact of various iodine concentrations of iohexol and iodixanol contrast media on image reconstruction techniques in a vascular-specific contrast media phantom: quantitative and qualitative image quality assessment.

Autor: Saade C; Faculty of Health Sciences, Medical Imaging Sciences, American University of Beirut Medical Center, P.O. Box: 11-0236, Riad El-Solh, Beirut, 1107 2020, Lebanon., Karout L; Faculty of Health Sciences, Medical Imaging Sciences, American University of Beirut Medical Center, P.O. Box: 11-0236, Riad El-Solh, Beirut, 1107 2020, Lebanon., El Asmar K; Department of Epidemiology and Population Health Sciences, Faculty of Health Sciences, American University of Beirut Medical Center, P.O. Box: 11-0236, Riad El-Solh, Beirut, 1107 2020, Lebanon., Naffaa L; Diagnostic Radiology Department, American University of Beirut Medical Center, P.O. Box: 11-0236, Riad El-Solh, Beirut, 1107 2020, Lebanon., El Merhi F; Diagnostic Radiology Department, American University of Beirut Medical Center, P.O. Box: 11-0236, Riad El-Solh, Beirut, 1107 2020, Lebanon., Salman R; Diagnostic Radiology Department, American University of Beirut Medical Center, P.O. Box: 11-0236, Riad El-Solh, Beirut, 1107 2020, Lebanon., Abi-Ghanem AS; Diagnostic Radiology Department, American University of Beirut Medical Center, P.O. Box: 11-0236, Riad El-Solh, Beirut, 1107 2020, Lebanon. aa277@aub.edu.lb.
Jazyk: angličtina
Zdroj: La Radiologia medica [Radiol Med] 2021 Feb; Vol. 126 (2), pp. 221-230. Date of Electronic Publication: 2020 Jul 15.
DOI: 10.1007/s11547-020-01253-4
Abstrakt: Purpose: The aim of our study is to investigate the impact of iodine quantification on image reconstruction when employing a vascular-specific contrast media phantom with varying iodine concentrations.
Materials and Methods: A 30-cm phantom simulating arterial and venous blood vessel diameters was manufactured. Small (9 mm) and medium (12 mm) cylinders contained iodine concentrations from 10 to 100% while large (21 mm) cylinders were in quartiles from 25 to 100% diluted in blood equivalent medium. Each phantom was filled with either iohexol 350 mgI/mL (Group A) or iodixanol 320 mgI/mL (Group B) and then scanned separately. For each group, tube potential (80-140 kVp) and current (50-400 mAs) were changed and all image series were reconstructed with filtered back projection (FBP), hybrid-based iterative reconstruction (HBIR) and model-based iterative reconstruction (MBIR). Mean opacification was measured in all groups. All data were compared employing an independent t test and Pearson's correlation. Visual grading characteristic (VGC) and Cohens' kappa analyses were performed.
Results: At 80 kVp, mean opacification using HBIR was significantly higher in Group B (2165 ± 1108 HU) than in Group A (2040 ± 1036 HU) (p < 0.009). At 140 kVp, MBIR and HBIR were greater in Group A (1704 ± 1033 HU and 1685 ± 1023 HU) versus Group B (1567 ± 1036 HU and 1567 ± 1034 HU) (p < 0.022). CNR using FBP, HBIR and MBIR was higher in Group B (46 ± 42 HU, 70 ± 163 HU and 83 ± 74 HU, respectively) than in Group A (43 ± 39 HU, 174 ± 130 HU and 80 ± 65 HU, respectively) (p < 0.0001-0.035). Qualitative image analysis demonstrated no difference in Cohen's kappa analysis. VGC was higher in Group A at all image reconstruction groups.
Conclusion: Iohexol outperforms iodixanol in observer performance when assessing image reconstruction techniques and iodine concentrations in a vascular-specific contrast media phantom.
Databáze: MEDLINE
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