An Atypical Presentation of Extrapulmonary Sarcoidosis.

Autor: Rawala MS; Department of Internal Medicine, WVU-Charleston Division, Charleston, WV, USA.; Department of Medicine, Rapides Regional Medical Center, Alexandria, LA, USA., Ahmed AS; Department of Medicine, Jinnah Medical & Dental College, Karachi, Pakistan., Helmick K; Department of Internal Medicine, WVU-Charleston Division, Charleston, WV, USA.
Jazyk: angličtina
Zdroj: Case reports in rheumatology [Case Rep Rheumatol] 2020 Jun 25; Vol. 2020, pp. 8840245. Date of Electronic Publication: 2020 Jun 25 (Print Publication: 2020).
DOI: 10.1155/2020/8840245
Abstrakt: Sarcoidosis is an idiopathic, chronic, multisystem, granulomatous, inflammatory disease involving almost all organs. Sarcoidosis can occur with an atypical presentation of hepatosplenic involvement, like in the case of our patient. In this case report, we present a rare case of extrapulmonary sarcoidosis with isolated involvement of the liver and spleen in a 39-year-old Caucasian female. There is a possibility of this isolated involvement of an organ in the complete absence of pulmonary disease, which makes the diagnosis of sarcoidosis very difficult as it is usually not suspected. Ultrasound and CT are important in ruling out other differential diagnoses, but a definitive diagnosis is possible only on histological examination, differentiating sarcoid lesions from tuberculosis , primary biliary cirrhosis, metastasis, malignancy, and other granulomatous infections or diseases. Hence, the most credible criterion for diagnosis remains histology. After diagnosis, regular follow-up for systemic manifestations is recommended. Asymptomatic patients with hepatosplenic sarcoidosis have a good prognosis without any medical intervention, while patients with abnormal labs or symptoms must commence treatment.
Competing Interests: The authors report no conflicts of interest regarding the content herein.
(Copyright © 2020 Muhammad Shabbir Rawala et al.)
Databáze: MEDLINE
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