| Autor: |
Ramzy RMR; 1National Nutrition Institute, General Organization for Teaching Hospitals and Institutes, Cairo, Egypt., Rabiee A; 2Ministry of Health and Population, Cairo, Egypt., Abd Elaziz KM; 3Department of Community, Environmental and Occupational Medicine, Faculty of Medicine, Ain Shams University, Cairo, Egypt., Campbell CH; 4Center for Tropical and Emerging Global Diseases, University of Georgia, Athens, Georgia., Kittur N; 4Center for Tropical and Emerging Global Diseases, University of Georgia, Athens, Georgia., Colley DG; 4Center for Tropical and Emerging Global Diseases, University of Georgia, Athens, Georgia.; 5Department of Microbiology, University of Georgia, Athens, Georgia., Haggag AA; 2Ministry of Health and Population, Cairo, Egypt. |
| Jazyk: |
angličtina |
| Zdroj: |
The American journal of tropical medicine and hygiene [Am J Trop Med Hyg] 2020 Oct; Vol. 103 (4), pp. 1572-1577. |
| DOI: |
10.4269/ajtmh.20-0156 |
| Abstrakt: |
We assessed the feasibility of using a test, treat, track, test, and treat (5T) active surveillance strategy to identify and treat individuals with schistosomiasis in three very low-prevalence villages in Kafr El Sheikh Governorate, Egypt. Primary index cases (PICs) were identified using the point-of-care circulating cathodic antigen (POC-CCA) assay in schools, in rural health units (retesting individuals with positive Kato-Katz examinations over the previous 6 months), and at potential water transmission sites identified by PICs and field observations. Primary cases identified potential second-generation cases-people with whom they shared water activities-who were then tracked, tested, and treated if infected. Those sharing water activities with second-generation cases were also tested. The yield of PICs from the three venues were 128 of 3,576 schoolchildren (3.6%), 42 of 696 in rural health units (6.0%), and 83 of 1,156 at water contact sites (7.2%). There were 118 second- and 19 third-generation cases identified. Persons testing positive were treated with praziquantel. Of 388 persons treated, 368 (94.8%) had posttreatment POC-CCA tests 3-4 weeks after treatment, and 81.8% (301) became negative. The 67 persons remaining positive had negative results after a second treatment. Therefore, all those found positive, treated, and followed up were negative following one or two treatments. Analysis of efforts as expressed in person-hours indicates that 4,459 person-hours were required for these 5T activities, with nearly 65% of that time spent carrying out interviews, treatments, and evaluations following treatment. The 5T strategy appears feasible and acceptable as programs move toward elimination. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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