Impact of Puberty in Pediatric Migraine: A Pilot Prospective Study.

Autor:	Fonseca E; Headache Unit. Neurology Department, Hospital Universitari Vall d'Hebron, Barcelona, Spain., Torres-Ferrús M; Headache Unit. Neurology Department, Hospital Universitari Vall d'Hebron, Barcelona, Spain., Gallardo VJ; Headache Research Group, Vall d'Hebron Research Institute (VHIR), Universitat Autònoma de Barcelona, Barcelona, Spain., Macaya A; Department of Pediatric Neurology, Hospital Universitari Vall d'Hebron, Barcelona, Spain., Pozo-Rosich P; Headache Unit. Neurology Department, Hospital Universitari Vall d'Hebron, Barcelona, Spain. ppozo@vhebron.net.
Jazyk:	angličtina
Zdroj:	Journal of clinical neurology (Seoul, Korea) [J Clin Neurol] 2020 Jul; Vol. 16 (3), pp. 416-422.
DOI:	10.3988/jcn.2020.16.3.416
Abstrakt:	Background and Purpose: The short-term evolution of pediatric migraine remains unclear. We aimed to describe the evolution of migraine before and after puberty and its relationship with lifestyle habits. Methods: We prospectively selected prepuberal patients from a neuropediatric unit who had a migraine diagnosis. Their medical history, migraine characteristics and impact, and lifestyle habits were recorded at the baseline visit. After 2 years we performed a telephone follow-up assessment. Results: Nineteen patients were recruited (age 10.2±2.9 years, mean±SD; 57.9% female), of whom 27.5% had migraine with aura. The accompanying symptoms had changed at the follow-up, with significantly higher prevalence rates of dizziness (44.4% vs. 88.9%), vertigo (11.1% vs. 66.7%), mood changes (38.9% vs 83.3%), confusion (5.6% vs. 77.8%), and allodynia (27.8% vs. 61.1%). Sleep disturbances (5.6% vs. 38.9%) and schedule changes (0% vs. 38.9%) increased significantly as triggers. Prodromal symptoms became more prevalent (16.7% vs. 50%), with a higher proportion of sleep disturbances reported (50.0% vs. 87.5%). Conclusions: Prodromal symptoms increase in pediatric migraine after 2 years, and some trigger factors for migraine become more prevalent, including sleep disturbances. New accompanying symptoms are also identified. These changes provide information about how migraine changes during puberty along with physical and lifestyle changes, and represent a dynamic physiopathological process that deserves more research. Competing Interests: MTF reports personal fees and non-financial support from Allergan, Novartis and Chiesi outside the submitted work. (Copyright © 2020 Korean Neurological Association.)
Databáze:	MEDLINE
Externí odkaz:	Zobrazit plný text záznamu