Clinical Frailty Scale
| Autor: | Mendiratta P; University of Arkansas, Latif R; Columbia University / Jacobi Med Center |
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| Jazyk: | angličtina |
| Zdroj: | 2021 Jan. |
| Abstrakt: | Across the globe, in all countries, the number of older adults is increasing. These increases in the elderly population are making frailty an increasing concern for the healthcare system. Frailty is a multidimensional geriatric syndrome, which is characterized by an increased vulnerability to various external stressors. Frailty is associated with multiple adverse outcomes, including mortality, admissions to nursing homes, and falls. It will continue to place a substantial and increasing burden on public health and healthcare systems.[1] Frailty is the result of cumulative cellular damage from diverse etiologies over the life of the individual. Typical aging results in loss of some homeostatic reserve in physiological systems. However, despite the loss of these reserves, individuals still function well with aging. Any homeostatic perturbation in these reserves will result in the older adult decompensating and thus causing frailty. The silent precursor to frailty is pre-frailty or latent frailty. Frailty happens from latent frailty whenever external stressors (e.g., acute illness, injury, or mental stress) occur in the older adult.[2] Frailty can develop due to factors such as (i) socio-demographic influences (e.g. poverty, living alone, low education level); (ii) psychological factors (e.g. depression); (iii) nutritional issues (e.g. malnutrition); (iv) polypharmacy; (v) diseases and complications (inflammatory states, cancer, endocrine disorders, dementia); and (v) low physical activity.[3] Despite the importance of frailty, there is currently no internationally recognized standard definition given its complex etiology; definitions used by different frailty researchers; and the inherent difficulty in distinguishing frailty from both aging and disability. Irrespective of definitions, it is clear that frailty is an important geriatric syndrome, which is dynamic, fluctuates over time, and reflects multisystem dysfunction. Given its importance, since the mid-1990s, frailty combination scores have been developed, wherein a constellation of frailty manifestations was grouped to be able to quantify the degree of disability from frailty.[4] (Copyright © 2021, StatPearls Publishing LLC.) |
| Databáze: | MEDLINE |
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