Diagnostic Challenges in Chondroblastic Maxillary Osteosarcoma: A Case Report.

Autor: Rajab MK; Otolaryngology-Head and Neck Surgery, Ministry of Health, Makkah, SAU., I Awad B; Otolaryngology-Head and Neck Surgery, King Saud bin Abdulaziz University for Health Sciences, King Abdullah International Medical Research Center, Jeddah, SAU., Al-Hakami HA; Otolaryngology, King Saud bin Abdulaziz University for Health Sciences, King Abdullah International Medical Research Center, Ministry of National Guard Health Affairs, Jeddah, SAU., Al-Maghrabi H; Pathology, King Faisal Specialist Hospital and Research Center, Jeddah, SAU.
Jazyk: angličtina
Zdroj: Cureus [Cureus] 2020 Jun 02; Vol. 12 (6), pp. e8418. Date of Electronic Publication: 2020 Jun 02.
DOI: 10.7759/cureus.8418
Abstrakt: The diagnosis of craniofacial osteosarcoma can be quite challenging, and the condition often goes unrecognized for a considerable period of time. In this report, we discuss the case of a 21-year old woman who presented with a one-year history of a small swelling over the left maxillary alveolar ridge. Upon further investigation, the histopathological examination showed high-grade chondroblastic osteosarcoma. The option of four cycles of neoadjuvant chemotherapy regimen preoperatively was chosen, and left inferior maxillectomy was performed along with reconstruction with obturator prosthesis. This case highlights the difficulties encountered in such rare cases of craniofacial osteosarcomas both in terms of the delay in the establishment of the diagnosis as well as management protocol. A high index of suspicion is required in cases of craniofacial osteosarcoma and early surgical resection with adequate safety margins is warranted.
Competing Interests: The authors have declared that no competing interests exist.
(Copyright © 2020, Rajab et al.)
Databáze: MEDLINE