The role of dopamine in reward-related behavior: shining new light on an old debate.

Autor: Wang AR; Department of Psychiatry and Behavioral Sciences, Stanford University, Stanford, California., Groome A; Department of Psychiatry and Behavioral Sciences, Stanford University, Stanford, California., Taniguchi L; Department of Psychiatry and Behavioral Sciences, Stanford University, Stanford, California., Eshel N; Department of Psychiatry and Behavioral Sciences, Stanford University, Stanford, California., Bentzley BS; Department of Psychiatry and Behavioral Sciences, Stanford University, Stanford, California.
Jazyk: angličtina
Zdroj: Journal of neurophysiology [J Neurophysiol] 2020 Aug 01; Vol. 124 (2), pp. 309-311. Date of Electronic Publication: 2020 Jul 08.
DOI: 10.1152/jn.00323.2020
Abstrakt: The role dopamine plays in reward-related behaviors has been debated for decades. Heymann et al. (Heymann G, Jo YS, Reichard KL, McFarland N, Chavkin C, Palmiter RD, Soden ME, Zweifel LS. Neuron 105: 909-920, 2020) identify subpopulations of dopamine-producing neurons that separately mediate reward association and motivation. Their results help demonstrate that dopamine signaling may partake in both reinforcement learning and incentive salience functions, instantiated by neuropeptide-defined subpopulations of the ventral tegmental area with different projection targets.
Databáze: MEDLINE