| Autor: |
Sousa-Junior LPB; Departamento de Zootecnia, Universidade Federal da Bahia, Salvador, BA, Brazil., Meira AN; Departamento de Zootecnia, Universidade Federal da Bahia, Salvador, BA, Brazil., Azevedo HC; Embrapa Tabuleiros Costeiros, Brasilia, SE, Brazil., Muniz EN; Embrapa Tabuleiros Costeiros, Brasilia, SE, Brazil., Coutinho LL; Departamento de Zootecnia, Universidade de São Paulo, Piracicaba, SP, Brazil., Mourão GB; Departamento de Zootecnia, Universidade de São Paulo, Piracicaba, SP, Brazil., Leão AG; Instituto de Ciências Agrárias e Tecnológicas, Universidade Federal de Mato Grosso, Rondonópolis, MT, Brazil., Pedrosa VB; Departamento de Zootecnia, Universidade Estadual de Ponta Grossa, Ponta Grossa, PR, Brazil., Pinto LFB; Departamento de Zootecnia, Universidade Federal da Bahia, Salvador, BA, Brazil. |
| Abstrakt: |
Myostatin and MyoD family genes play vital roles in myogenesis and this study aimed to identify association of variants in MyoD1 , MyoG , MyF5 , MyF6 , and MSTN genes with meat traits in Santa Inês sheep. A dataset with 44 variants and records of seven meat traits in 192 lambs (pH0, pH24, a*, b*, L*, tenderness assessed by shear force, and water-holding capacity) was used. Single-locus and haplotype association analyses were performed, and the significance threshold was established according to Bonferroni's method. Single-locus analysis revealed two associations at a Bonferroni level, where the variant c.935-185C > G in MyoD1 had an additive effect (-4.31 ± 1.08 N) on tenderness, while the variant c.464 + 185G > A in MyoG had an additive effect (-2.86 ± 0.64) on a*. Additionally, the haplotype replacement GT > AC in MSTN was associated with pH0 (1.26 ± 0.31), pH24 (1.07 ± 0.27), a* (-1.40 ± 0.51), and tenderness (3.83 ± 1.22 N), while the replacement GT > AG in MyoD1 was associated with pH0 (1.43 ± 0.26), pH24 (1.25 ± 0.22), b* (-1.06 ± 0.39), and tenderness (-4.13 ± 1.16 N). Our results have demonstrated that some variants in MyoG , MyF6 , MyoD1 , and MSTN can be associated with physicochemical meat traits in Santa Inês sheep. |
