Extended endonasal endoscopic approach for anterior midline skull base lesions.

Autor: Özer Mİ; Department of Neurosurgery, University of Health Sciences, Gulhane School of Medicine, Ankara, Turkey., Kutlay AM; Department of Neurosurgery, University of Health Sciences, Gulhane School of Medicine, Ankara, Turkey., Durmaz MO; Department of Neurosurgery, University of Health Sciences, Gulhane School of Medicine, Ankara, Turkey., Kirik A; Department of Neurosurgery, University of Health Sciences, Gulhane School of Medicine, Ankara, Turkey., Yaşar S; Department of Neurosurgery, University of Health Sciences, Gulhane School of Medicine, Ankara, Turkey., Tehli Ö; Department of Neurosurgery, University of Health Sciences, Gulhane School of Medicine, Ankara, Turkey., Kural C; Department of Neurosurgery, University of Health Sciences, Gulhane School of Medicine, Ankara, Turkey., Temiz NÇ; Department of Neurosurgery, University of Health Sciences, Gulhane School of Medicine, Ankara, Turkey., Durmaz A; Department of Otorhinolaryngology, University of Health Sciences, Gulhane School of Medicine, Ankara, Turkey., Ezgu MC; Department of Neurosurgery, University of Health Sciences, Gulhane School of Medicine, Ankara, Turkey., Daneyemez MK; Department of Neurosurgery, University of Health Sciences, Gulhane School of Medicine, Ankara, Turkey., Izci Y; Department of Neurosurgery, University of Health Sciences, Gulhane School of Medicine, Ankara, Turkey. Electronic address: yusufizci@yahoo.com.
Jazyk: angličtina
Zdroj: Clinical neurology and neurosurgery [Clin Neurol Neurosurg] 2020 Sep; Vol. 196, pp. 106024. Date of Electronic Publication: 2020 Jun 20.
DOI: 10.1016/j.clineuro.2020.106024
Abstrakt: Aim: In recent years, extended endoscopic endonasal approach (EEEA) has been used as an alternative to transcranial approaches in the treatment of anterior midline skull base lesions. We retrospectively reviewed our cases operated using this technique and compared the results with current literature.
Method: The data of 24 patients who were operated using EEEA in our department between 2010-2018 were retrospectively analyzed. The lesions were located in the midline between the posterior wall of the frontal sinus and tuberculum sella. Tumor locations, histopathological diagnoses, surgical techniques, outcomes and complications were documented.
Results: Eleven patients were female and 13 were male. Their ages ranged between 18-75 years (mean 40.5 years). Considering their locations; 12 were in the anterior fossa (50 %), 7 were in the tuberculum sella (29.1 %), and 5 were in both anatomic sites (20.8 %). Histopathologically, our series consisted of 15 meningiomas, 6 osteomas, 2 dermoid tumors and 1 metastatic carcinoma. We achieved gross total resection in 75 % of our patients. Ten patients presented with visual complaints and 7 of them improved postoperatively. Postoperative cerebrospinal fluid leakage (CSF) was observed in 3 patients and one of them developed meningitis and subsequently died of sepsis.
Conclusion: Although the number of cases is low, EEEA seems like a safe, effective and well-tolerated treatment modality for anterior midline skull base lesions. But strict preventive measures should be taken for a possible CSF leak.
(Copyright © 2020 Elsevier B.V. All rights reserved.)
Databáze: MEDLINE
Externí odkaz: