Relevance of the Endoscopic Evaluation in the Diagnosis of Bladder Pain Syndrome/Interstitial Cystitis.

Autor: Morlacco A; Urology Clinic, Department of Surgery, Oncology and Gastroenterology, University of Padova, Padova, Italy. Electronic address: alessandro.morlacco@unipd.it., Mancini M; Urology Clinic, Department of Surgery, Oncology and Gastroenterology, University of Padova, Padova, Italy., Soligo M; Urology Clinic, Department of Surgery, Oncology and Gastroenterology, University of Padova, Padova, Italy., Zattoni F; Urology Clinic, University of Udine and University Hospital 'Santa Maria della Misericordia', Udine, Italy., Calpista A; Urology Clinic, Department of Surgery, Oncology and Gastroenterology, University of Padova, Padova, Italy., Vizzielli G; Division of Gynecologic Oncology, Fondazione Policlinico Universitario 'Agostino Gemelli' IRCCS, Rome, Italy., Patti R; Urology Clinic, Department of Surgery, Oncology and Gastroenterology, University of Padova, Padova, Italy., Mandato FG; Urology Clinic, Department of Surgery, Oncology and Gastroenterology, University of Padova, Padova, Italy., Barneschi AC; Urology Clinic, Department of Surgery, Oncology and Gastroenterology, University of Padova, Padova, Italy., Zattoni F; Urology Clinic, Department of Surgery, Oncology and Gastroenterology, University of Padova, Padova, Italy., Iafrate M; Urology Clinic, Department of Surgery, Oncology and Gastroenterology, University of Padova, Padova, Italy., Dal Moro F; Urology Clinic, University of Udine and University Hospital 'Santa Maria della Misericordia', Udine, Italy.
Jazyk: angličtina
Zdroj: Urology [Urology] 2020 Oct; Vol. 144, pp. 106-110. Date of Electronic Publication: 2020 Jun 30.
DOI: 10.1016/j.urology.2020.06.032
Abstrakt: Objective: To assess the relevance of the endoscopic evaluation in clinically suspected cases of Bladder Pain Syndrome/Interstitial Cystitis (BPS/IC), using ESSIC criteria, established in 2008 by the European Society for the Study of Interstitial Cystitis (ESSIC).
Methods: We included all patients who underwent endoscopic evaluation between January 01, 2015 and October 31, 2019 for clinical suspicion of BPS/IC. Collected data included demographic and baseline clinical features, endoscopic appearance (prior and after hydrodistension), and bladder wall biopsy results, both defined according to ESSIC criteria. Data were cross tabulated to define ESSIC phenotypes, while subgroups and multivariate analyses were carried out to assess the influence of clinical variables on ESSIC phenotypes.
Results: Fifty-two subjects were included, mainly women (92%). Median age at evaluation was 45 (32.9-58.2) years. At hydrodistension, 21 patients (42%) had positive and 29 (58%) had negative findings. Grade 2-3 glomerulations were found in 18 patients, while Hunner lesions were reported only in 1 patient. Positive results at biopsy were found in 24 pts (51.1%), while negative in 23 (48.9%). Overall, the positive and negative concordance between hydrodistension and biopsy results was 78%. No significant differences in ESSIC subtypes were found after stratification based on clinical features and at multivariate analysis. Retrospective design is the main limitation.
Conclusion: Cystoscopy with hydrodistension and biopsy do have a role in the diagnostic pathway of BPS/IC. However, results should be considered in the clinical context of the individual patient.
(Copyright © 2020 Elsevier Inc. All rights reserved.)
Databáze: MEDLINE
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