From Skin to Brain: A Parkinson's Disease Patient Transplanted with His Own Cells.

Autor:	Parmar M; Developmental and Regenerative Neurobiology, Department of Experimental Medical Science, Wallenberg Neuroscience Center, Lund University, 22184 Lund, Sweden. Electronic address: malin.parmar@med.lu.se., Björklund A; Developmental and Regenerative Neurobiology, Department of Experimental Medical Science, Wallenberg Neuroscience Center, Lund University, 22184 Lund, Sweden. Electronic address: anders.bjorklund@med.lu.se.
Jazyk:	angličtina
Zdroj:	Cell stem cell [Cell Stem Cell] 2020 Jul 02; Vol. 27 (1), pp. 8-10.
DOI:	10.1016/j.stem.2020.06.008
Abstrakt:	In a pioneering study in New England Journal of Medicine, Schweitzer et al. (2020) report on a patient with Parkinson's disease who received a graft of dopamine neurons obtained from in vitro differentiated induced pluripotent stem cells, derived from the patient's own skin fibroblasts, showing the feasibility of autologous transplantation for dopamine cell replacement. Competing Interests: Declaration of Interests M.P. is the owner of Parmar Cells AB and co-inventor of the US patent application 15/093,927 owned by Biolamina AB, 16/610,787 owned by New York Stem Cell Foundation, and EP17181588 owned by Miltenyi Biotec. M.P. receives research funding from Novo Nordisk. (Copyright © 2020 Elsevier Inc. All rights reserved.)
Databáze:	MEDLINE
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