| Autor: |
Cochrane RVK; School of Chemistry and Chemical Engineering, Queen's University Belfast, David Keir Building, Stranmillis Road, Belfast, UKBT9 5AG. s.cochrane@qub.ac.uk., Alexander FM, Boland C, Fetics SK, Caffrey M, Cochrane SA |
| Jazyk: |
angličtina |
| Zdroj: |
Chemical communications (Cambridge, England) [Chem Commun (Camb)] 2020 Aug 07; Vol. 56 (61), pp. 8603-8606. Date of Electronic Publication: 2020 Jul 03. |
| DOI: |
10.1039/d0cc03388j |
| Abstrakt: |
Undecaprenol-containing glycolipids (UCGs) are essential precursors of bacterial glycopolymers and glycoproteins. We report a novel semi-synthetic strategy to prepare labelled UCGs directly from undecaprenol. This one-size-fits-all approach offers a concise and efficient method for obtaining labelled-UCGs, which will allow new mechanistic studies and inhibitor screens to be performed on novel antibiotic targets. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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