| Autor: |
Noordin NR; 1Department of Parasitology, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia., Lee PY; 1Department of Parasitology, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia., Mohd Bukhari FD; 1Department of Parasitology, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia., Fong MY; 1Department of Parasitology, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia., Abdul Hamid MH; 2Vector Borne Disease Sector, Ministry of Health, Putrajaya, Malaysia., Jelip J; 2Vector Borne Disease Sector, Ministry of Health, Putrajaya, Malaysia., Mudin RN; 2Vector Borne Disease Sector, Ministry of Health, Putrajaya, Malaysia., Lau YL; 1Department of Parasitology, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia. |
| Abstrakt: |
Asymptomatic and/or low-density malaria infection has been acknowledged as an obstacle to achieving a malaria-free country. This study aimed to determine the prevalence of asymptomatic and/or low-density malaria infection in previously reported malarious localities using nested PCR in four states, namely, Johor, Pahang, Kelantan, and Selangor, between June 2019 and January 2020. Blood samples ( n = 585) were collected and were extracted using a QIAamp blood kit. The DNA was concentrated and subjected to nested PCR. Thin and thick blood smears were examined as well. Of the 585 samples collected, 19 were positive: 10 for Plasmodium knowlesi , eight for Plasmodium vivax , and one for Plasmodium ovale . Asymptomatic and/or low-density malaria infection is a threat to malaria elimination initiatives. Eliminating countries should develop guidance policy on the importance of low-density malaria infection which includes detection and treatment policy. |
