Ultrasensitive determination of sulfathiazole using a molecularly imprinted electrochemical sensor with CuS microflowers as an electron transfer probe and Au@COF for signal amplification.

Autor: Sun Y; Key Laboratory of Food Processing Technology and Quality Control in Shandong Province, College of Food Science and Engineering, Shandong Agricultural University, Taian 271018, People's Republic of China., Gao H; Forestry College, Shandong Agricultural University, Taian 271018, People's Republic of China., Xu L; Key Laboratory of Food Processing Technology and Quality Control in Shandong Province, College of Food Science and Engineering, Shandong Agricultural University, Taian 271018, People's Republic of China., Waterhouse GIN; School of Chemical Sciences, The University of Auckland, Auckland 1142, New Zealand., Zhang H; College of Life Science, Shandong Normal University, Jinan 250014, People's Republic of China., Qiao X; Key Laboratory of Food Processing Technology and Quality Control in Shandong Province, College of Food Science and Engineering, Shandong Agricultural University, Taian 271018, People's Republic of China., Xu Z; Key Laboratory of Food Processing Technology and Quality Control in Shandong Province, College of Food Science and Engineering, Shandong Agricultural University, Taian 271018, People's Republic of China. Electronic address: zhixiangxu@sina.com.
Jazyk: angličtina
Zdroj: Food chemistry [Food Chem] 2020 Dec 01; Vol. 332, pp. 127376. Date of Electronic Publication: 2020 Jun 25.
DOI: 10.1016/j.foodchem.2020.127376
Abstrakt: In this work, a molecularly imprinted sensor employing copper sulfide (CuS) as a novel signal probe was successfully developed for ultrasensitive and selective determination of sulfathiazole (STZ). The reduction signals of Cu 2+ produced in the process of electron transfer of CuS containing large amounts of Cu 2+ are easy to be captured, which provide high electrochemical signals. Moreover, gold nanoparticles@covalent organic framework with excellent conductivity was introduced on the electrode surface for signal amplification and facilitating electron transfer processes of CuS. Under optimized testing conditions, the proposed sensor offered a linear DPV response to STZ over a very wide concentration range (1.0 × 10 -4 to 1.0 × 10 -11 mol L -1 ), with a limit of detection of 4.3 × 10 -12 mol L -1 . Fodder and mutton samples spiked with STZ were analyzed using this sensor, and the satisfactory recoveries ranging from 83.0% to 107.2% were obtained. In addition, the proposed sensor was used to determine the concentration of STZ in chicken liver and pork liver, with quantification results being near identical to those determined by high-performance liquid chromatography.
Competing Interests: Declaration of Competing Interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.
(Copyright © 2020 Elsevier Ltd. All rights reserved.)
Databáze: MEDLINE
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