Isolated pulmonary vasculitis associated with nilotinib use: A case report.

Autor: Morris NT; Division of Rheumatology, University of California, Los Angeles, David Geffen School of Medicine, California, USA., Taylor MB; Division of Rheumatology, University of California, Los Angeles, David Geffen School of Medicine, California, USA., Hacobian M; University of California, Los Angeles, David Geffen School of Medicine, California, USA., Olevsky OM; Division of Hematology, University of California, Los Angeles, David Geffen School of Medicine, California, USA., Kermani TA; Division of Rheumatology, University of California, Los Angeles, David Geffen School of Medicine, California, USA.
Jazyk: angličtina
Zdroj: Leukemia research reports [Leuk Res Rep] 2020 Jun 18; Vol. 14, pp. 100214. Date of Electronic Publication: 2020 Jun 18 (Print Publication: 2020).
DOI: 10.1016/j.lrr.2020.100214
Abstrakt: An association between tyrosine-kinase inhibitor therapy for chronic myeloid leukemia and vascular adverse events including peripheral arterial disease, coronary artery disease, and pulmonary hypertension has been described. We present a patient who developed isolated pulmonary artery vasculitis resulting in left pulmonary artery stenosis, in addition to left coronary artery stenosis while on nilotinib. While monitoring for cardiovascular events is important, clinicians should also recognize possible drug-induced vasculitis during chronic nilotinib therapy.
(© 2020 Published by Elsevier Ltd.)
Databáze: MEDLINE