Total and regional bone mineral density are associated with cellular health in older men and women.

Autor: Antunes M; Metabolism, Nutrition, and Exercise Laboratory, Physical Education and Sport Center, Londrina State University, Londrina, PR, Brazil. Electronic address: melissa.antunes@hotmail.com., Cyrino ES; Metabolism, Nutrition, and Exercise Laboratory, Physical Education and Sport Center, Londrina State University, Londrina, PR, Brazil. Electronic address: edilsoncyrino@gmail.com., Silva DRP; Department of Physical Education, Federal University of Sergipe, São Cristovão, SE, Brazil. Electronic address: danilorpsilva@gmail.com., Tomeleri CM; Metabolism, Nutrition, and Exercise Laboratory, Physical Education and Sport Center, Londrina State University, Londrina, PR, Brazil; Exercise Physiology Laboratory, Faculty of Physical Education, University of Campinas, Campinas, SP, Brazil. Electronic address: crisielitomeleri@gmail.com., Nabuco HCG; Metabolism, Nutrition, and Exercise Laboratory, Physical Education and Sport Center, Londrina State University, Londrina, PR, Brazil; Federal Institute of Science and Technology of Mato Grosso, Cuiabá, MT, Brazil. Electronic address: hellenclair@hotmail.com., Cavalcante EF; Metabolism, Nutrition, and Exercise Laboratory, Physical Education and Sport Center, Londrina State University, Londrina, PR, Brazil. Electronic address: edilainefungari@gmail.com., Cunha PM; Metabolism, Nutrition, and Exercise Laboratory, Physical Education and Sport Center, Londrina State University, Londrina, PR, Brazil. Electronic address: pcunha88@hotmail.com., Cyrino LT; Metabolism, Nutrition, and Exercise Laboratory, Physical Education and Sport Center, Londrina State University, Londrina, PR, Brazil. Electronic address: leticia.cyrino@gmail.com., Dos Santos L; Metabolism, Nutrition, and Exercise Laboratory, Physical Education and Sport Center, Londrina State University, Londrina, PR, Brazil. Electronic address: le_edfisica@hotmail.com., Silva AM; Exercise and Health Laboratory, CIPER, Faculdade de Motricidade Humana, Universidade de Lisboa, Portugal. Electronic address: analiza@fmh.utl.pt., Sardinha LB; Exercise and Health Laboratory, CIPER, Faculdade de Motricidade Humana, Universidade de Lisboa, Portugal. Electronic address: lsardinha@fmh.utl.pt.
Jazyk: angličtina
Zdroj: Archives of gerontology and geriatrics [Arch Gerontol Geriatr] 2020 Sep - Oct; Vol. 90, pp. 104156. Date of Electronic Publication: 2020 Jun 15.
DOI: 10.1016/j.archger.2020.104156
Abstrakt: Objective: This study aimed to investigate the relationship between crude bioimpedance variables with bone mineral density (BMD) in older adults.
Method: One hundred eighty-four older men and women (≥ 60 years old) composed the sample. BMD (whole-body) was measured through dual-energy X-ray absorptiometry. Bioimpedance spectroscopy was used to estimate whole-body resistance and reactance as well as to calculate the phase angle (PhA) and fat-free mass (FFM). Age, gender, body mass, FFM, height, calcium intake, vitamin D intake, number of fractures, number of diseases, and number of medications were included as covariates in the regression analyses.
Results: BMD fractions were significantly (P < 0.01) associated with PhA (femur: r = 0.524; neck: r = 0.450; and forearm: r = 0.437). Independently of age, body mass, FFM, calcium intake, vitamin D, number of diseases, fratures and medications, PhA remains a significant explanator of the variability of total (β = 0.22; P < 0.001), femur (β = 0.10; P = 0.018), and neck BMD (β = 0.07; P = 0.05) for men, and total (β = 0.08; P = 0.002), femur (β = 0.06; P = 0.005), neck (β = 0.04; P = 0.03), and forearm BMD (β = 0.05; P = 0.004) for women.
Conclusion: Our results suggest that a higher PhA is associated with BMD in older men and women fractions regardless of relevant covariates highlighting the biological meaning of this simple and crude bioimpedance-based measure in the elderly population.
Competing Interests: Declaration of Competing Interest None.
(Copyright © 2020. Published by Elsevier B.V.)
Databáze: MEDLINE
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