[European registry Helicobacter pylori (Hp-EuReg): how has clinical practice changed in Russia from 2013 to 2018 years].

Autor:	Bordin DS; A.S. Loginov Moscow Clinical Research and Practical Center of the Department of Health of Moscow., Embutnieks YV; A.S. Loginov Moscow Clinical Research and Practical Center of the Department of Health of Moscow., Vologzhanina LG; Gastrocenter., Ilchishina TA; SM-Clinic., Voynovan IN; A.S. Loginov Moscow Clinical Research and Practical Center of the Department of Health of Moscow., Sarsenbaeva AS; South Ural State Medical University of the Ministry of Health of the Russian Federation., Zaitsev OV; First Clinical Medical Centre., Alekseenko SA; Far-Eastern State Medical University of the Ministry of Health of the Russian Federation., Abdulkhakov RA; Kazan State Medical University of the Ministry of Health of the Russian Federation., Dehnich NN; Smolensk State Medical University of the Ministry of Health of the Russian Federation., Osipenko MF; Novosibirsk State Medical University of the Ministry of Health of the Russian Federation., Livzan MA; Omsk State Medical University of the Ministry of Health of the Russian Federation., Tsukanov VV; Research Institute for Medical Problems of the North., Burkov SG; Polyclinic № 3 of the Department for Presidential Affairs of the Russian Federation., Bakulina NV; I.I. Mechnikov North-Western State Medical University of the Ministry of Health of the Russian Federation., Plotnikova EY; Kemerovo State Medical Academy of the Ministry of Health of the Russian Federation., Tarasova LV; Republican Gastroenterology Center, Republican Clinical Hospital of the Ministry of Health and Social Development of Chuvashia.; I.N. Ulyanov Chuvash State University., Maev IV; A.I. Evdokimov Moscow State University of Medicine and Dentistry of the Ministry of Health of the Russian Federation., Kucheryavyi YA; A.I. Evdokimov Moscow State University of Medicine and Dentistry of the Ministry of Health of the Russian Federation., Baryshnikova NV; I.P. Pavlov First Saint Petersburg State Medical University of the Ministry of Health of the Russian Federation., Butov MA; I.P. Pavlov Ryazan State Medical University of the Ministry of Health of the Russian Federation., Kolbasnikov SV; Tver State Medical University of the Ministry of Health of the Russian Federation., Pakhomova AL; Saratov State Clinical Hospital №5., Zhestkova TV; I.P. Pavlov Ryazan State Medical University of the Ministry of Health of the Russian Federation., Baranovsky AY; Saint Petersburg State University., Abdulhakov SR; Kazan State Medical University of the Ministry of Health of the Russian Federation.; Kazan Federal University., Ageeva EA; Municipal outpatient clinic №3, Ministry of Health of Khabarovsk Region., Lyalyukova EA; Omsk State Medical University of the Ministry of Health of the Russian Federation., Vasyutin AV; Research Institute for Medical Problems of the North., Golubev NN; Polyclinic № 3 of the Department for Presidential Affairs of the Russian Federation., Savilova IV; I.I. Mechnikov North-Western State Medical University of the Ministry of Health of the Russian Federation., Morkovkina LV; Republican Gastroenterology Center, Republican Clinical Hospital of the Ministry of Health and Social Development of Chuvashia., Kononova AG; Tver State Medical University of the Ministry of Health of the Russian Federation., Megraud F; Laboratoire de Bactériologie, Hôpital Pellegrin., O'Morain C; Department of Gastroenterology, Tallaght Hospital/Trinity College Dublin., Ramas M; Gastroenterology Unit, Hospital Universitario de La Princesa, Instituto de Investigación Sanitaria Princesa (IIS-IP), Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas (CIBERehd), and Universidad Autónoma de Madrid (UAM)., Nyssen OP; Gastroenterology Unit, Hospital Universitario de La Princesa, Instituto de Investigación Sanitaria Princesa (IIS-IP), Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas (CIBERehd), and Universidad Autónoma de Madrid (UAM)., McNicholl AG; Gastroenterology Unit, Hospital Universitario de La Princesa, Instituto de Investigación Sanitaria Princesa (IIS-IP), Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas (CIBERehd), and Universidad Autónoma de Madrid (UAM)., Gisbert JP; Gastroenterology Unit, Hospital Universitario de La Princesa, Instituto de Investigación Sanitaria Princesa (IIS-IP), Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas (CIBERehd), and Universidad Autónoma de Madrid (UAM).
Jazyk:	ruština
Zdroj:	Terapevticheskii arkhiv [Ter Arkh] 2019 Feb 15; Vol. 91 (2), pp. 16-24. Date of Electronic Publication: 2019 Feb 15.
DOI:	10.26442/00403660.2019.02.000156
Abstrakt:	The multicenter prospective observational study initiated by the European Helicobacter and Microbiota Study Group (EHMSG) is conducted in 27 countries in Europe. The data from the Russian part of the European registry for the management of Helicobacter pylori infection (European Registry on the management of Helicobacter pylori infection, protocol: "Hp-EuReg") allows us to analyze the real clinical practice of diagnosis and treatment of H. pylori and compare it with international recommendations. Materials and Methods: A comparative analysis of the data entered in the register by the Russian research centers "Hp-EuReg", in the period from 2013 to 2018, was conducted. Results and Discussion: Invasive diagnostic methods prevail for the primary diagnosis of H. pylori [histology - 20.3% (in 2013 year) - 43.9% (in 2018 year), rapid urease test - 31.7% and 47.8% respectively]. The most popular mode of eradication therapy is a 10-day triple therapy (62.8-76.2%), the effectiveness of which does not exceed 79% (per protocol). Invasive tests (histology) are the leading method for control the effectiveness of therapy, however, there is a tendency towards a wider use of non-invasive methods (H. pylori stool antigen - from 17% in 2013 to 29.3% in 2018 and urea breath test from 6.9 to 18.3%, respectively). Serological test to control the effectiveness of eradication is still used from 8.2% (2013) to 6.1% (2018). Eradication therapy was not performed in 28% of patients throughout the entire observation period. Conclusion: In Russia, despite approved domestic and international recommendations, deviations in clinical practice persist, both during eradication therapy and in monitoring the effectiveness of eradication therapy.
Databáze:	MEDLINE
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