[Features of hemorrhagic fever with renal syndrome with diabetes mellitus].

Autor:	Manakhov KM; Izhevsk State Medical Academy., Kamenshchikova TM; Izhevsk State Medical Academy., Tsarenko OE; Izhevsk State Medical Academy., Borodina ZI; Izhevsk State Medical Academy., Bagautdinova LI; Izhevsk State Medical Academy., Sargsyan DS; Izhevsk State Medical Academy., Malinin OV; Izhevsk State Medical Academy., Dudarev MV; Izhevsk State Medical Academy., Shklyaev AE; Izhevsk State Medical Academy., Platonov AE; Central Research Institute of Epidemiology., Maleev VV; Central Research Institute of Epidemiology.
Jazyk:	ruština
Zdroj:	Terapevticheskii arkhiv [Ter Arkh] 2019 Nov 15; Vol. 91 (11), pp. 10-15. Date of Electronic Publication: 2019 Nov 15.
DOI:	10.26442/00403660.2019.11.000359
Abstrakt:	Aim: Diabetes mellitus (DM) is known to be a risk factor in adverse outcomes and complications in many infectious diseases. In the combination of hemorrhagic fever with renal syndrome (HFRS) and DM there are mutually exclusive pathogenetic States - hyperosmolarity, characteristic of DM is layered on the reduction of osmotic blood pressure in HFRS. Under these conditions, the effect of one disease (DM) on the clinical manifestations of another (HFRS) is not obvious. The aim of the work is to find out the clinical features during hfps in patients with DM. Materials and Methods: The study is based on the results of the retrospective studies "case - control" - studied the information contained in medical records of patient (form 003/u), who suffered HFRS in 2006-2018. The Selection of cards produced randomly. In the end, there were formed two groups: the first - 981 patient who suffered HFRS and had no signs of diabetes; the second, 33 patients who suffered HFRS on the background of previously existing (28 people), or the first identified (5) diabetes. Results: With a combination of HFRS and DM, a mild course of the disease is 2.5 times more common, there are no severe forms. Among this group of patients, complications are almost 10 times less common, less likely to develop infectious - toxic shock, acute kidney damage (class F by RIFLE), pulmonary edema. The combination of DM and HFRS is manifested by less high and prolonged fever, less high levels of urea and creatinine in the blood. Conclusion: HFRS in combination with DM is easier, apparently, high osmolarity of the blood is a stabilizing factor during the disease.
Databáze:	MEDLINE
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