Parasitic Infection Surveillance in Mississippi Delta Children.

Autor: Bradbury RS; 1Division of Parasitic Diseases and Malaria, Parasitic Diseases Branch, Center for Global Health, Centers for Disease Control and Prevention, Atlanta, Georgia.; 2School of Health and Life Sciences, Federation University, Berwick Campus, Melbourne, Australia., Arguello I; 3Department of Pediatrics, Division of Infectious Diseases, Children's of Mississippi, Jackson, Mississippi., Lane M; 1Division of Parasitic Diseases and Malaria, Parasitic Diseases Branch, Center for Global Health, Centers for Disease Control and Prevention, Atlanta, Georgia., Cooley G; 1Division of Parasitic Diseases and Malaria, Parasitic Diseases Branch, Center for Global Health, Centers for Disease Control and Prevention, Atlanta, Georgia., Handali S; 1Division of Parasitic Diseases and Malaria, Parasitic Diseases Branch, Center for Global Health, Centers for Disease Control and Prevention, Atlanta, Georgia., Dimitrova SD; 1Division of Parasitic Diseases and Malaria, Parasitic Diseases Branch, Center for Global Health, Centers for Disease Control and Prevention, Atlanta, Georgia., Nascimento FS; 1Division of Parasitic Diseases and Malaria, Parasitic Diseases Branch, Center for Global Health, Centers for Disease Control and Prevention, Atlanta, Georgia., Jameson S; 3Department of Pediatrics, Division of Infectious Diseases, Children's of Mississippi, Jackson, Mississippi., Hellmann K; 3Department of Pediatrics, Division of Infectious Diseases, Children's of Mississippi, Jackson, Mississippi., Tharp M; 4Division of Genetics, Department of Pediatrics, University of Mississippi Medical Center, Jackson, Mississippi.; 5The Delta Mercy Project, School of Nursing, University of Mississippi Medical Center, Jackson, Mississippi., Byers P; 6Mississippi State Department of Health, Jackson, Mississippi., Montgomery SP; 1Division of Parasitic Diseases and Malaria, Parasitic Diseases Branch, Center for Global Health, Centers for Disease Control and Prevention, Atlanta, Georgia., Haynie L; 5The Delta Mercy Project, School of Nursing, University of Mississippi Medical Center, Jackson, Mississippi., Kirmse B; 4Division of Genetics, Department of Pediatrics, University of Mississippi Medical Center, Jackson, Mississippi., Pilotte N; 7Department of Biological Sciences, Smith College, Northampton, Massachusetts.; 8Program in Molecular and Cellular Biology, University of Massachusetts, Amherst, Massachusetts., Williams SA; 7Department of Biological Sciences, Smith College, Northampton, Massachusetts.; 8Program in Molecular and Cellular Biology, University of Massachusetts, Amherst, Massachusetts., Hobbs CV; 3Department of Pediatrics, Division of Infectious Diseases, Children's of Mississippi, Jackson, Mississippi.; 9Department of Microbiology, University of Mississippi Medical Center, Jackson, Mississippi.
Jazyk: angličtina
Zdroj: The American journal of tropical medicine and hygiene [Am J Trop Med Hyg] 2020 Sep; Vol. 103 (3), pp. 1150-1153.
DOI: 10.4269/ajtmh.20-0026
Abstrakt: Some recent studies suggest ongoing transmission of parasitic diseases in the American South; however, surveys in Mississippi children are lacking. We enrolled 166 children (median age 8 years, range 4-13 years) from the Mississippi Delta region and carried out multi-parallel real-time polymerase chain reaction (PCR) for Necator americanus , Ascaris lumbricoides , and Strongyloides stercoralis on their stool samples. Dried blood spots were obtained for multiplex serology antibody detection. Of 166 children, all reported having flushable toilets, 11% had soil exposure, and 34% had a pet dog or cat. None had prior diagnosis or treatment of parasitic disease. Multi-parallel real-time PCRs were negative on the 89 stool DNA extracts available for testing. Dried blood spot testing of all 166 children determined the seroprevalence of IgG antibodies to Toxocara spp . (3.6%), Cryptosporidium (2.4%), S. stercoralis , Fasciola hepatica , and Giardia duodenalis (all 0%). In conclusion, parasitic infections and exposure were scarce in this population. Larger studies of at-risk populations are needed.
Databáze: MEDLINE