Autor: |
Berdiaev SIu, Danilova OE |
Jazyk: |
ruština |
Zdroj: |
Farmakologiia i toksikologiia [Farmakol Toksikol] 1988 Jan-Feb; Vol. 51 (1), pp. 44-6. |
Abstrakt: |
During experiments on strips of the frog ventricular myocardium and venous sinuses it was shown that marcaine and its derivative suppress the spontaneous activity of pacemaker cells, increase the threshold of occurrence of potentials of action and the minimal period of assimilation of forced excitations. These effects are dose-dependent and increase at a rise of stimulation frequency. Its derivative was inferior by effect intensity as compared with marcaine, it failed to exert a strong suppressive effect on the amplitude and duration of potentials of action. |
Databáze: |
MEDLINE |
Externí odkaz: |
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