Patterns of practice for adaptive and real-time radiation therapy (POP-ART RT) part I: Intra-fraction breathing motion management.

Autor: Anastasi G; St. Luke's Cancer Centre, Royal Surrey Foundation Trust, Radiotherapy Physics, Guildford, United Kingdom. Electronic address: gail.distefano@nhs.net., Bertholet J; The Institute of Cancer Research and The Royal Marsden NHS Foundation Trust, Joint Department of Physics, London, United Kingdom; Division of Medical Radiation Physics, Department of Radiation Oncology, Inselspital, Bern University Hospital, Switzerland., Poulsen P; Aarhus University Hospital, Department of Oncology and Danish Center for Particle Therapy, Aarhus, Denmark., Roggen T; Varian Medical Systems Imaging Laboratory GmbH, Applied Research, Dättwil AG, Switzerland., Garibaldi C; European Institute of Oncology IRCCS, IEO-Unit of Radiation Research, Milan, Italy., Tilly N; Elekta Instruments AB, Stockholm, Sweden; Medical Radiation Physics, Department of Immunology, Genetics and Pathology, Uppsala University, Sweden., Booth JT; Royal North Shore Hospital, Northern Sydney Cancer Centre, Australia., Oelfke U; The Institute of Cancer Research and The Royal Marsden NHS Foundation Trust, Joint Department of Physics, London, United Kingdom., Heijmen B; Erasmus MC Cancer Institute, Department of Radiation Oncology, Rotterdam, Netherlands., Aznar MC; Division of Cancer Sciences, Faculty of Biology, Medicine and Health, The University of Manchester, The Christie NHS Foundation Trust, Manchester, United Kingdom; Nuffield Department of Population Health, University of Oxford, United Kingdom.
Jazyk: angličtina
Zdroj: Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology [Radiother Oncol] 2020 Dec; Vol. 153, pp. 79-87. Date of Electronic Publication: 2020 Jun 23.
DOI: 10.1016/j.radonc.2020.06.018
Abstrakt: Purpose: The POP-ART RT study aims to determine to what extent and how intra-fractional real-time respiratory motion management (RRMM) and plan adaptation for inter-fractional anatomical changes (ART), are used in clinical practice and to understand barriers to implementation. Here we report on part I: RRMM.
Material and Methods: A questionnaire was distributed worldwide to assess current clinical practice, wishes for expansion or new implementation and barriers to implementation. RRMM was defined as inspiration/expiration gating in free-breathing or breath-hold, or tracking where the target and the beam are continuously realigned.
Results: The questionnaire was completed by 200 centres from 41 countries. RRMM was used by 68% of respondents ('users') for a median (range) of 2 (1-6) tumour sites. Eighty-one percent of users applied inspiration breath-hold in at least one tumour site (breast: 96%). External marker was used to guide RRMM by 61% of users. KV/MV imaging was frequently used for liver and pancreas (with fiducials) and for lung (with or without fiducials). Tracking was mainly performed on robotic linacs with hybrid internal-external monitoring. For breast and lung, approximately 75% of respondents used or wished to implement RRMM, which was lower for liver (44%) and pancreas (27%). Seventy-one percent of respondents wished to implement RRMM for a new tumour site. Main barriers were human/financial resources and capacity on the machine.
Conclusion: Sixty-eight percent of respondents used RRMM and 71% wished to implement RRMM for a new tumour site. The main barriers to implementation were human/financial resources and capacity on treatment machines.
(Copyright © 2020 The Authors. Published by Elsevier B.V. All rights reserved.)
Databáze: MEDLINE
Externí odkaz: