| Autor: |
Pinheiro ALB; Center of Biophotonics, School of Dentistry, Federal University of Bahia - UFBA, Av. Araújo Pinho, 62, Canela, Salvador, BA, 40110-150, Brazil. albp@ufba.br.; National Institute of Basic Optics and Applied to Life Sciences, Physics Institute of São Carlos, University of São Paulo, Av. Trabalhador São-Carlense, 400, Parque Arnold Schimidt, Sao Carlos, SP, 13566-590, Brazil. albp@ufba.br.; Biomedical Engineering Institute, Universidade Brasil, Sao Paulo, SP, 08230-030, Brazil. albp@ufba.br., Soares LGP; Center of Biophotonics, School of Dentistry, Federal University of Bahia - UFBA, Av. Araújo Pinho, 62, Canela, Salvador, BA, 40110-150, Brazil.; National Institute of Basic Optics and Applied to Life Sciences, Physics Institute of São Carlos, University of São Paulo, Av. Trabalhador São-Carlense, 400, Parque Arnold Schimidt, Sao Carlos, SP, 13566-590, Brazil.; Department of Biointeraction, Institute of Health Science, Federal University of Bahia, Reitor Miguel Calmon Ave, S/N, Salvador, BA, 40110-100, Brazil., da Silva ACP; Center of Biophotonics, School of Dentistry, Federal University of Bahia - UFBA, Av. Araújo Pinho, 62, Canela, Salvador, BA, 40110-150, Brazil., Santos NRS; Center of Biophotonics, School of Dentistry, Federal University of Bahia - UFBA, Av. Araújo Pinho, 62, Canela, Salvador, BA, 40110-150, Brazil., da Silva APLT; Center of Biophotonics, School of Dentistry, Federal University of Bahia - UFBA, Av. Araújo Pinho, 62, Canela, Salvador, BA, 40110-150, Brazil., Neves BLRC; Center of Biophotonics, School of Dentistry, Federal University of Bahia - UFBA, Av. Araújo Pinho, 62, Canela, Salvador, BA, 40110-150, Brazil., Soares AP; Center of Biophotonics, School of Dentistry, Federal University of Bahia - UFBA, Av. Araújo Pinho, 62, Canela, Salvador, BA, 40110-150, Brazil., Gerbi MEMM; Faculty of Dentistry, Pernambuco State University, Av. Gal. Newton Cavalcanti, 1650 - Tabatinga, Camaragibe, PE, 54756-220, Brazil., Dos Santos JN; Laboratory of Surgical Pathology, School of Dentistry, Federal University of Bahia - UFBA, Av. Araújo Pinho, 62, Canela, Salvador, BA, 40110-150, Brazil. |
| Abstrakt: |
The repair of large bone defects is lengthy and complex. Both biomaterials and phototherapy have been used to improve bone repair. We aimed to describe histologically the repair of tibial fractures treated by wiring (W), irradiated or not, with laser (λ780 nm, 70 mW, CW, spot area of 0.5 cm 2 , 20.4 J/cm 2 (4 × 5.1 J/cm 2 , Twin Flex Evolution®, MM Optics, Sao Carlos, SP, Brazil) per session, 300 s, 142.8 J/cm 2 per treatment) or LED (λ850 ± 10 nm, 150 mW, spot area of 0.5 cm 2 , 20.4 J/cm 2 per session, 64 s, 142.8 J/cm 2 per treatment, Fisioled® , MM Optics, Sao Carlos, Sao Paulo, Brazil) and associated or not to the use of mineral trioxide aggregate (MTA, Angelus®, Londrina, PR, Brazil). Inflammation was discrete on groups W and W + LEDPT and absent on the others. Phototherapy protocols started immediately before suturing and repeated at every other day for 15 days. Collagen deposition intense on groups W + LEDPT, W + BIO-MTA + LaserPT and W + BIO-MTA + LEDPT and discrete or moderate on the other groups. Reabsorption was discrete on groups W and W + LEDPT and absent on the other groups. Neoformation varied greatly between groups. Most groups were partial and moderately filed with new-formed bone (W, W + LaserPT, W + LEDPT, W + BIO-MTA + LEDPT). On groups W + BIO-MTA and W + BIO-MTA + LaserPT bone, neoformation was intense and complete. Our results are indicative that the association of MTA and PBMT (λ = 780 nm) improves the repair of complete tibial fracture treated with wire osteosynthesis in a rodent model more efficiently than LED (λ = 850 ± 10 nm). |
Full text from SpringerLink