Cellular angiofibroma of the orbit.

Autor: Hötte GJ; Department of Oculoplastic, Orbital and Lacrimal Surgery, The Rotterdam Eye Hospital, Rotterdam, The Netherlands., Verdijk RM; Department of Oculoplastic, Orbital and Lacrimal Surgery, The Rotterdam Eye Hospital, Rotterdam, The Netherlands.; Department of Pathology, Section Ophthalmic Pathology, Erasmus MC, University Medical Center Rotterdam, The Netherlands., Gardeniers M; Department of Radiology and Nuclear Medicine, Erasmus MC, University Medical Center Rotterdam, The Netherlands., Paridaens D; Department of Oculoplastic, Orbital and Lacrimal Surgery, The Rotterdam Eye Hospital, Rotterdam, The Netherlands.; Department of Ophthalmology, Orbital Service, Erasmus MC, University Medical Center Rotterdam, The Netherlands.
Jazyk: angličtina
Zdroj: Orbit (Amsterdam, Netherlands) [Orbit] 2021 Aug; Vol. 40 (4), pp. 329-332. Date of Electronic Publication: 2020 Jun 23.
DOI: 10.1080/01676830.2020.1782443
Abstrakt: Cellular angiofibroma is a benign mesenchymal tumor most commonly located in the distal genital tract of both men and women. Although extragenital locations have been reported rarely, this is the first report of cellular angiofibroma of the orbit. A 58-year-old man presented with a mass in the left superomedial orbit since 2 years. Magnetic resonance imaging showed a well-demarcated lesion with a homogeneous intermediate signal intensity on both T1- and T2-weighted images, homogeneous contrast enhancement and high signal intensity on diffusion-weighted images. Complete excision was performed through a medial upper eyelid crease incision. Histopathology showed a vascular CD34-positive and STAT6-negative spindle cell tumor with monoallelic loss of FOXO1, indicating cellular angiofibroma.
Databáze: MEDLINE
Externí odkaz:
Nepřihlášeným uživatelům se plný text nezobrazuje