Management of stage 0 medication-related osteonecrosis of the jaw with hyperbaric oxygen therapy: a case report and review of the literature.

Autor: Lin LJ; Medical Student, NYU School of Medicine, New York, New York U.S., Alfonso AR; Hansjörg Wyss Department of Plastic Surgery, NYU Langone Health, New York, New York U.S., Ross FL; Department of Surgery, NYU Langone Health, New York, New York U.S., Chiu ES; Hansjörg Wyss Department of Plastic Surgery, NYU Langone Health, New York, New York U.S., Fleisher KE; Department of Oral and Maxillofacial Surgery, NYU College of Dentistry, New York, New York .U.S.; Hansjörg Wyss Department of Plastic Surgery, NYU Langone Health, New York, New York U.S.
Jazyk: angličtina
Zdroj: Undersea & hyperbaric medicine : journal of the Undersea and Hyperbaric Medical Society, Inc [Undersea Hyperb Med] 2020 Second Quarter; Vol. 47 (2), pp. 241-251.
DOI: 10.22462/04.06.2020.10
Abstrakt: The definition of medication-related osteonecrosis of the jaw (MRONJ) includes a stage 0 presentation where exposed bone, the hallmark of this condition, is absent. Numerous management strategies have been recommended for MRONJ including hyperbaric oxygen (HBO2) therapy. This report describes a 64-year-old woman with stage 0 MRONJ of the bilateral mandible, refractory to clindamycin and local debridement, who was subsequently managed successfully with amoxicillin/clavulanate and HBO2 therapy. The authors also explore the current literature on the pathophysiology of MRONJ and the potential role of hyperbaric oxygen in its treatment.
Competing Interests: The authors of this paper declare no conflicts of interest exist with this submission.
(Copyright© Undersea and Hyperbaric Medical Society.)
Databáze: MEDLINE